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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VPS11
All Species:
31.52
Human Site:
Y256
Identified Species:
53.33
UniProt:
Q9H270
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H270
NP_068375.3
941
107837
Y256
V
A
G
D
E
C
V
Y
L
Y
Q
P
D
E
R
Chimpanzee
Pan troglodytes
XP_508805
941
107763
Y256
V
A
G
D
E
C
V
Y
L
Y
Q
P
D
E
R
Rhesus Macaque
Macaca mulatta
XP_001101032
941
107684
Y256
V
A
G
D
E
C
V
Y
L
Y
Q
P
D
E
R
Dog
Lupus familis
XP_546492
941
107605
Y256
V
A
G
D
E
C
V
Y
L
Y
Q
P
D
E
R
Cat
Felis silvestris
Mouse
Mus musculus
Q91W86
941
107751
Y256
V
A
G
D
E
C
V
Y
L
Y
Q
P
D
E
R
Rat
Rattus norvegicus
NP_001101608
878
101153
R238
P
K
S
E
F
T
S
R
D
S
Q
N
S
D
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_417847
929
106402
Y245
V
A
G
N
E
C
V
Y
L
Y
Q
P
D
E
R
Frog
Xenopus laevis
NP_001088406
914
104616
Y241
V
A
S
N
E
C
V
Y
L
Y
Q
P
D
E
R
Zebra Danio
Brachydanio rerio
XP_002663611
927
106605
Y241
V
A
G
D
D
C
V
Y
L
Y
Q
P
D
E
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393972
1079
122741
I240
M
I
G
R
N
D
A
I
Y
C
Y
T
P
D
G
Nematode Worm
Caenorhab. elegans
Q09600
980
111990
A242
S
T
G
Q
L
I
V
A
S
R
E
M
L
F
F
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002321189
962
108854
I245
M
S
D
R
L
E
L
I
I
G
R
P
E
A
V
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_027676
932
105695
G238
D
R
S
E
L
I
V
G
R
P
E
A
V
Y
F
Baker's Yeast
Sacchar. cerevisiae
P12868
1029
117459
I244
I
C
C
L
S
N
F
I
E
F
F
S
S
S
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99.2
98
N.A.
97.9
91.5
N.A.
N.A.
83.5
77.4
74.1
N.A.
N.A.
41.3
26.4
N.A.
Protein Similarity:
100
99.8
99.5
98.9
N.A.
98.9
92.4
N.A.
N.A.
91.5
86.7
85.2
N.A.
N.A.
58.2
46.9
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
6.6
N.A.
N.A.
93.3
86.6
93.3
N.A.
N.A.
6.6
13.3
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
26.6
N.A.
N.A.
100
93.3
100
N.A.
N.A.
20
20
N.A.
Percent
Protein Identity:
38.4
N.A.
N.A.
40.8
20.8
N.A.
Protein Similarity:
57.3
N.A.
N.A.
60.8
39.4
N.A.
P-Site Identity:
6.6
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
46.6
N.A.
N.A.
20
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
58
0
0
0
0
8
8
0
0
0
8
0
8
0
% A
% Cys:
0
8
8
0
0
58
0
0
0
8
0
0
0
0
0
% C
% Asp:
8
0
8
43
8
8
0
0
8
0
0
0
58
15
0
% D
% Glu:
0
0
0
15
50
8
0
0
8
0
15
0
8
58
0
% E
% Phe:
0
0
0
0
8
0
8
0
0
8
8
0
0
8
15
% F
% Gly:
0
0
65
0
0
0
0
8
0
8
0
0
0
0
15
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
8
0
0
0
15
0
22
8
0
0
0
0
0
0
% I
% Lys:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
8
% K
% Leu:
0
0
0
8
22
0
8
0
58
0
0
0
8
0
0
% L
% Met:
15
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
0
0
0
15
8
8
0
0
0
0
0
8
0
0
0
% N
% Pro:
8
0
0
0
0
0
0
0
0
8
0
65
8
0
0
% P
% Gln:
0
0
0
8
0
0
0
0
0
0
65
0
0
0
0
% Q
% Arg:
0
8
0
15
0
0
0
8
8
8
8
0
0
0
58
% R
% Ser:
8
8
22
0
8
0
8
0
8
8
0
8
15
8
0
% S
% Thr:
0
8
0
0
0
8
0
0
0
0
0
8
0
0
0
% T
% Val:
58
0
0
0
0
0
72
0
0
0
0
0
8
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
58
8
58
8
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _