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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CARD9
All Species:
23.03
Human Site:
T300
Identified Species:
63.33
UniProt:
Q9H257
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H257
NP_434700.2
536
62241
T300
D
H
Q
E
Q
A
N
T
I
F
S
L
R
K
D
Chimpanzee
Pan troglodytes
XP_001171164
536
62152
T300
D
H
Q
E
Q
A
N
T
I
F
S
L
R
K
D
Rhesus Macaque
Macaca mulatta
XP_001095549
535
62146
T300
D
H
Q
E
Q
A
N
T
I
F
S
L
R
K
D
Dog
Lupus familis
XP_849271
646
74152
T410
G
Q
Q
E
Q
A
S
T
I
L
S
L
R
K
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8CIS0
1159
134022
K322
D
R
Q
E
L
V
N
K
I
Y
N
L
Q
E
E
Rat
Rattus norvegicus
Q9EPY0
536
62613
T300
E
H
Q
E
Q
A
S
T
I
F
S
L
R
K
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_425329
560
65975
T325
E
R
Q
D
L
L
N
T
L
Y
H
L
R
K
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q7SXE4
760
84597
S447
D
L
Q
Q
Q
A
K
S
S
R
S
A
A
E
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LME2
871
99988
L621
I
Q
E
E
H
S
S
L
I
L
S
L
R
E
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
97
71.8
N.A.
24
86.1
N.A.
N.A.
58
N.A.
21.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.4
98.1
75.6
N.A.
34.5
91.2
N.A.
N.A.
73.5
N.A.
38.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
73.3
N.A.
40
86.6
N.A.
N.A.
40
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
80
N.A.
73.3
100
N.A.
N.A.
73.3
N.A.
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
39
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
66.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
67
0
0
0
0
0
12
12
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
56
0
0
12
0
0
0
0
0
0
0
0
0
0
56
% D
% Glu:
23
0
12
78
0
0
0
0
0
0
0
0
0
34
34
% E
% Phe:
0
0
0
0
0
0
0
0
0
45
0
0
0
0
0
% F
% Gly:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
45
0
0
12
0
0
0
0
0
12
0
0
0
0
% H
% Ile:
12
0
0
0
0
0
0
0
78
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
12
12
0
0
0
0
0
67
0
% K
% Leu:
0
12
0
0
23
12
0
12
12
23
0
89
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
56
0
0
0
12
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
23
89
12
67
0
0
0
0
0
0
0
12
0
0
% Q
% Arg:
0
23
0
0
0
0
0
0
0
12
0
0
78
0
0
% R
% Ser:
0
0
0
0
0
12
34
12
12
0
78
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
67
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
23
0
0
0
0
12
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _