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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
P2RY12
All Species:
20.61
Human Site:
T76
Identified Species:
50.37
UniProt:
Q9H244
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H244
NP_073625.1
342
39439
T76
S
D
L
L
M
I
L
T
F
P
F
K
I
L
S
Chimpanzee
Pan troglodytes
XP_001145406
342
39408
T76
S
D
L
L
M
I
L
T
F
P
F
K
I
L
S
Rhesus Macaque
Macaca mulatta
XP_001107340
342
39491
T76
S
D
L
L
M
I
L
T
F
P
F
K
I
L
S
Dog
Lupus familis
XP_852662
333
38100
K78
M
T
L
M
L
P
F
K
I
L
S
D
S
H
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9CPV9
347
39455
T82
S
D
L
L
M
I
L
T
F
P
F
K
I
L
S
Rat
Rattus norvegicus
Q9EPX4
343
39029
T82
S
D
L
L
M
I
L
T
F
P
F
K
I
L
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516794
337
38721
M78
A
D
L
I
M
T
L
M
L
P
F
K
I
L
T
Chicken
Gallus gallus
P32250
308
35579
P68
L
L
F
V
F
T
L
P
F
R
I
Y
Y
F
V
Frog
Xenopus laevis
P79928
537
62006
S95
S
D
T
L
Y
V
L
S
L
P
T
L
V
Y
Y
Zebra Danio
Brachydanio rerio
A5PLE7
368
41686
A79
S
D
I
L
F
S
L
A
L
P
L
R
V
V
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
98.2
46.2
N.A.
86.4
86
N.A.
47.9
25.4
20.6
23.1
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.7
99.1
63.7
N.A.
91.9
91.5
N.A.
64.9
49.1
35.9
47
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
6.6
N.A.
100
100
N.A.
60
13.3
33.3
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
20
N.A.
100
100
N.A.
80
20
53.3
60
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
80
0
0
0
0
0
0
0
0
0
10
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
10
0
20
0
10
0
60
0
60
0
0
10
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% H
% Ile:
0
0
10
10
0
50
0
0
10
0
10
0
60
0
0
% I
% Lys:
0
0
0
0
0
0
0
10
0
0
0
60
0
0
0
% K
% Leu:
10
10
70
70
10
0
90
0
30
10
10
10
0
60
10
% L
% Met:
10
0
0
10
60
0
0
10
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
10
0
10
0
80
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
10
0
10
0
0
0
% R
% Ser:
70
0
0
0
0
10
0
10
0
0
10
0
10
0
50
% S
% Thr:
0
10
10
0
0
20
0
50
0
0
10
0
0
0
10
% T
% Val:
0
0
0
10
0
10
0
0
0
0
0
0
20
10
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
10
0
0
0
0
0
0
10
10
10
20
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _