Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: POLR2J3 All Species: 42.12
Human Site: T76 Identified Species: 71.28
UniProt: Q9H1A7 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H1A7 NP_001091084.1 115 13092 T76 K I I I R V Q T T P D Y S P Q
Chimpanzee Pan troglodytes XP_001135267 398 41732 T316 K I I I E X Q T T P D Y S P Q
Rhesus Macaque Macaca mulatta XP_001114618 191 20609 T151 K I I I R V Q T T P D Y S P Q
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus O08740 117 13233 T77 K I I I R V Q T T P D Y S P Q
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514119 117 13370 T77 K I I I R V Q T T P D Y S P Q
Chicken Gallus gallus
Frog Xenopus laevis Q5XK67 114 13106 A76 Q T R N G I P A V E P F R R G
Zebra Danio Brachydanio rerio Q6DRI4 112 12737 A75 Q T R D G V P A S E P L R N G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VJE4 117 13367 T77 K F V I R I Q T T A D Y S P Q
Honey Bee Apis mellifera XP_624001 117 13510 T77 K F V I R I Q T T S D Y T P H
Nematode Worm Caenorhab. elegans Q9XVH6 122 13678 T76 K I L L R I Q T T N N T T P A
Sea Urchin Strong. purpuratus XP_001197448 117 13241 T77 K F V L R V Q T T P D Y S P Q
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001142057 120 14102 T77 K I I V R I H T T S Q S S P T
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q38859 116 13545 T77 K I I V R I H T T S Q S S P M
Baker's Yeast Sacchar. cerevisiae P38902 120 13597 T77 R F K L R I Q T T E G Y D P K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 25.3 54.4 N.A. N.A. 88.8 N.A. N.A. 86.3 N.A. 27.8 29.5 N.A. 70 70.9 60.6 76.9
Protein Similarity: 100 26.3 56.5 N.A. N.A. 92.3 N.A. N.A. 89.7 N.A. 48.7 44.3 N.A. 82 83.7 72.9 86.3
P-Site Identity: 100 86.6 100 N.A. N.A. 100 N.A. N.A. 100 N.A. 0 6.6 N.A. 73.3 60 46.6 80
P-Site Similarity: 100 86.6 100 N.A. N.A. 100 N.A. N.A. 100 N.A. 20 20 N.A. 86.6 80 80 93.3
Percent
Protein Identity: N.A. 47.5 N.A. 45.6 48.3 N.A.
Protein Similarity: N.A. 67.5 N.A. 68.1 62.5 N.A.
P-Site Identity: N.A. 53.3 N.A. 53.3 40 N.A.
P-Site Similarity: N.A. 66.6 N.A. 66.6 66.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 15 0 8 0 0 0 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 8 0 0 0 0 0 0 58 0 8 0 0 % D
% Glu: 0 0 0 0 8 0 0 0 0 22 0 0 0 0 0 % E
% Phe: 0 29 0 0 0 0 0 0 0 0 0 8 0 0 0 % F
% Gly: 0 0 0 0 15 0 0 0 0 0 8 0 0 0 15 % G
% His: 0 0 0 0 0 0 15 0 0 0 0 0 0 0 8 % H
% Ile: 0 58 50 50 0 50 0 0 0 0 0 0 0 0 0 % I
% Lys: 79 0 8 0 0 0 0 0 0 0 0 0 0 0 8 % K
% Leu: 0 0 8 22 0 0 0 0 0 0 0 8 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % M
% Asn: 0 0 0 8 0 0 0 0 0 8 8 0 0 8 0 % N
% Pro: 0 0 0 0 0 0 15 0 0 43 15 0 0 86 0 % P
% Gln: 15 0 0 0 0 0 72 0 0 0 15 0 0 0 50 % Q
% Arg: 8 0 15 0 79 0 0 0 0 0 0 0 15 8 0 % R
% Ser: 0 0 0 0 0 0 0 0 8 22 0 15 65 0 0 % S
% Thr: 0 15 0 0 0 0 0 86 86 0 0 8 15 0 8 % T
% Val: 0 0 22 15 0 43 0 0 8 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 65 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _