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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
METTL9
All Species:
20
Human Site:
Y188
Identified Species:
33.85
UniProt:
Q9H1A3
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H1A3
NP_001070648.1
318
36536
Y188
W
Q
L
Q
K
K
K
Y
R
V
L
G
I
N
E
Chimpanzee
Pan troglodytes
XP_001160038
277
32344
N154
K
Y
R
V
L
G
I
N
E
W
Q
N
T
G
F
Rhesus Macaque
Macaca mulatta
XP_001086688
323
36436
S189
N
G
L
L
G
R
G
S
M
F
V
F
S
P
D
Dog
Lupus familis
XP_536936
277
32398
N154
K
Y
R
V
L
G
I
N
E
W
Q
K
T
G
F
Cat
Felis silvestris
Mouse
Mus musculus
Q9EPL4
318
36407
Y188
W
Q
L
Q
K
K
K
Y
R
V
L
G
I
N
E
Rat
Rattus norvegicus
NP_001156636
318
36423
Y188
W
Q
L
Q
K
K
K
Y
R
V
L
G
I
N
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508171
357
41002
V200
Y
H
S
F
V
S
S
V
F
S
L
F
M
S
R
Chicken
Gallus gallus
Q5ZMH6
321
36990
Y191
W
Q
L
Q
K
K
K
Y
R
V
L
G
I
N
E
Frog
Xenopus laevis
NP_001079600
315
36737
Y186
W
Q
L
Q
K
K
K
Y
R
V
L
N
I
D
E
Zebra Danio
Brachydanio rerio
NP_001070810
234
26336
I111
S
S
I
F
S
P
I
I
S
R
T
S
I
N
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611846
305
34724
E181
L
N
F
N
V
I
T
E
I
D
G
L
Q
N
L
Honey Bee
Apis mellifera
XP_623513
379
42710
F205
W
A
L
A
K
R
K
F
T
V
L
D
V
E
K
Nematode Worm
Caenorhab. elegans
NP_508880
311
35470
N185
Y
S
P
G
K
L
L
N
D
L
W
N
V
A
R
Sea Urchin
Strong. purpuratus
XP_001188574
325
37619
T182
D
G
W
S
Q
E
K
T
G
H
A
Y
D
M
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.9
78.9
83.6
N.A.
97.1
97.4
N.A.
61
86.9
72.9
39.9
N.A.
32.3
35.8
37.1
46.7
Protein Similarity:
100
84.9
79.2
84.2
N.A.
99.3
99
N.A.
64.4
90.6
83.6
49.6
N.A.
50
52.2
53.7
62.7
P-Site Identity:
100
0
6.6
0
N.A.
100
100
N.A.
6.6
100
86.6
13.3
N.A.
6.6
40
6.6
6.6
P-Site Similarity:
100
0
26.6
0
N.A.
100
100
N.A.
26.6
100
93.3
20
N.A.
6.6
66.6
26.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
8
0
0
0
0
0
0
8
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
0
0
0
0
8
8
0
8
8
8
8
% D
% Glu:
0
0
0
0
0
8
0
8
15
0
0
0
0
8
36
% E
% Phe:
0
0
8
15
0
0
0
8
8
8
0
15
0
0
15
% F
% Gly:
0
15
0
8
8
15
8
0
8
0
8
29
0
15
8
% G
% His:
0
8
0
0
0
0
0
0
0
8
0
0
0
0
0
% H
% Ile:
0
0
8
0
0
8
22
8
8
0
0
0
43
0
0
% I
% Lys:
15
0
0
0
50
36
50
0
0
0
0
8
0
0
8
% K
% Leu:
8
0
50
8
15
8
8
0
0
8
50
8
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
8
0
0
0
8
8
0
% M
% Asn:
8
8
0
8
0
0
0
22
0
0
0
22
0
43
0
% N
% Pro:
0
0
8
0
0
8
0
0
0
0
0
0
0
8
0
% P
% Gln:
0
36
0
36
8
0
0
0
0
0
15
0
8
0
0
% Q
% Arg:
0
0
15
0
0
15
0
0
36
8
0
0
0
0
15
% R
% Ser:
8
15
8
8
8
8
8
8
8
8
0
8
8
8
0
% S
% Thr:
0
0
0
0
0
0
8
8
8
0
8
0
15
0
0
% T
% Val:
0
0
0
15
15
0
0
8
0
43
8
0
15
0
8
% V
% Trp:
43
0
8
0
0
0
0
0
0
15
8
0
0
0
0
% W
% Tyr:
15
15
0
0
0
0
0
36
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _