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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
METTL9
All Species:
17.58
Human Site:
T220
Identified Species:
29.74
UniProt:
Q9H1A3
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.31
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H1A3
NP_001070648.1
318
36536
T220
D
R
C
D
Q
P
L
T
L
L
K
D
I
R
S
Chimpanzee
Pan troglodytes
XP_001160038
277
32344
R186
L
T
L
L
K
D
I
R
S
V
L
E
P
T
R
Rhesus Macaque
Macaca mulatta
XP_001086688
323
36436
G221
L
D
L
G
A
G
D
G
E
V
T
K
I
M
S
Dog
Lupus familis
XP_536936
277
32398
R186
L
T
L
L
K
D
I
R
S
V
L
E
P
T
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9EPL4
318
36407
T220
D
R
C
D
Q
P
L
T
L
L
K
D
I
R
S
Rat
Rattus norvegicus
NP_001156636
318
36423
T220
D
R
C
D
Q
P
L
T
L
L
K
D
I
R
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508171
357
41002
K232
D
Q
F
Q
R
L
L
K
I
N
P
D
W
K
T
Chicken
Gallus gallus
Q5ZMH6
321
36990
T223
D
R
C
D
Q
P
L
T
V
L
K
D
T
R
S
Frog
Xenopus laevis
NP_001079600
315
36737
T218
D
R
C
H
Q
P
V
T
L
L
K
E
M
R
S
Zebra Danio
Brachydanio rerio
NP_001070810
234
26336
W143
L
L
R
I
G
P
D
W
R
A
Q
R
M
L
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611846
305
34724
A213
L
L
E
D
I
H
L
A
L
A
P
N
G
R
A
Honey Bee
Apis mellifera
XP_623513
379
42710
L237
R
C
D
R
P
N
T
L
L
R
R
L
K
S
S
Nematode Worm
Caenorhab. elegans
NP_508880
311
35470
R217
V
E
F
N
P
N
G
R
S
T
R
P
D
N
Y
Sea Urchin
Strong. purpuratus
XP_001188574
325
37619
P214
D
I
R
E
S
L
S
P
S
G
V
V
V
M
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.9
78.9
83.6
N.A.
97.1
97.4
N.A.
61
86.9
72.9
39.9
N.A.
32.3
35.8
37.1
46.7
Protein Similarity:
100
84.9
79.2
84.2
N.A.
99.3
99
N.A.
64.4
90.6
83.6
49.6
N.A.
50
52.2
53.7
62.7
P-Site Identity:
100
0
13.3
0
N.A.
100
100
N.A.
20
86.6
73.3
6.6
N.A.
26.6
13.3
0
6.6
P-Site Similarity:
100
26.6
20
26.6
N.A.
100
100
N.A.
53.3
93.3
93.3
20
N.A.
40
20
13.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
0
8
0
15
0
0
0
0
15
% A
% Cys:
0
8
36
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
50
8
8
36
0
15
15
0
0
0
0
36
8
0
8
% D
% Glu:
0
8
8
8
0
0
0
0
8
0
0
22
0
0
0
% E
% Phe:
0
0
15
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
8
8
8
8
8
0
8
0
0
8
0
0
% G
% His:
0
0
0
8
0
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
8
8
0
15
0
8
0
0
0
29
0
0
% I
% Lys:
0
0
0
0
15
0
0
8
0
0
36
8
8
8
0
% K
% Leu:
36
15
22
15
0
15
43
8
43
36
15
8
0
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
15
15
0
% M
% Asn:
0
0
0
8
0
15
0
0
0
8
0
8
0
8
0
% N
% Pro:
0
0
0
0
15
43
0
8
0
0
15
8
15
0
0
% P
% Gln:
0
8
0
8
36
0
0
0
0
0
8
0
0
0
0
% Q
% Arg:
8
36
15
8
8
0
0
22
8
8
15
8
0
43
15
% R
% Ser:
0
0
0
0
8
0
8
0
29
0
0
0
0
8
50
% S
% Thr:
0
15
0
0
0
0
8
36
0
8
8
0
8
15
8
% T
% Val:
8
0
0
0
0
0
8
0
8
22
8
8
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
8
0
0
0
0
8
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _