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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
METTL9
All Species:
21.82
Human Site:
T178
Identified Species:
36.92
UniProt:
Q9H1A3
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H1A3
NP_001070648.1
318
36536
T178
Y
A
T
E
L
S
E
T
M
I
W
Q
L
Q
K
Chimpanzee
Pan troglodytes
XP_001160038
277
32344
Q144
E
T
M
I
W
Q
L
Q
K
K
K
Y
R
V
L
Rhesus Macaque
Macaca mulatta
XP_001086688
323
36436
T179
F
S
L
F
M
S
R
T
S
I
N
G
L
L
G
Dog
Lupus familis
XP_536936
277
32398
Q144
E
T
M
I
W
Q
L
Q
K
K
K
Y
R
V
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9EPL4
318
36407
T178
Y
A
T
E
L
S
E
T
M
I
W
Q
L
Q
K
Rat
Rattus norvegicus
NP_001156636
318
36423
T178
Y
A
T
E
L
S
E
T
M
I
W
Q
L
Q
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508171
357
41002
I190
E
K
S
G
W
L
F
I
Q
L
Y
H
S
F
V
Chicken
Gallus gallus
Q5ZMH6
321
36990
T181
Y
A
T
E
L
S
E
T
M
I
W
Q
L
Q
K
Frog
Xenopus laevis
NP_001079600
315
36737
T176
Y
V
T
E
M
S
Q
T
M
I
W
Q
L
Q
K
Zebra Danio
Brachydanio rerio
NP_001070810
234
26336
S101
I
F
T
Q
L
Y
H
S
L
F
S
S
I
F
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611846
305
34724
L171
S
W
T
M
R
D
R
L
K
K
L
N
F
N
V
Honey Bee
Apis mellifera
XP_623513
379
42710
P195
Y
A
T
D
I
S
A
P
M
R
W
A
L
A
K
Nematode Worm
Caenorhab. elegans
NP_508880
311
35470
D175
V
T
A
F
N
L
L
D
R
H
Y
S
P
G
K
Sea Urchin
Strong. purpuratus
XP_001188574
325
37619
L172
S
Q
R
G
Y
K
I
L
P
I
D
G
W
S
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.9
78.9
83.6
N.A.
97.1
97.4
N.A.
61
86.9
72.9
39.9
N.A.
32.3
35.8
37.1
46.7
Protein Similarity:
100
84.9
79.2
84.2
N.A.
99.3
99
N.A.
64.4
90.6
83.6
49.6
N.A.
50
52.2
53.7
62.7
P-Site Identity:
100
0
26.6
0
N.A.
100
100
N.A.
0
100
80
13.3
N.A.
6.6
53.3
6.6
6.6
P-Site Similarity:
100
0
46.6
0
N.A.
100
100
N.A.
20
100
93.3
40
N.A.
6.6
66.6
13.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
36
8
0
0
0
8
0
0
0
0
8
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
8
0
8
0
0
8
0
0
0
0
% D
% Glu:
22
0
0
36
0
0
29
0
0
0
0
0
0
0
0
% E
% Phe:
8
8
0
15
0
0
8
0
0
8
0
0
8
15
0
% F
% Gly:
0
0
0
15
0
0
0
0
0
0
0
15
0
8
8
% G
% His:
0
0
0
0
0
0
8
0
0
8
0
8
0
0
0
% H
% Ile:
8
0
0
15
8
0
8
8
0
50
0
0
8
0
0
% I
% Lys:
0
8
0
0
0
8
0
0
22
22
15
0
0
0
50
% K
% Leu:
0
0
8
0
36
15
22
15
8
8
8
0
50
8
15
% L
% Met:
0
0
15
8
15
0
0
0
43
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
8
0
0
0
0
0
8
8
0
8
0
% N
% Pro:
0
0
0
0
0
0
0
8
8
0
0
0
8
0
0
% P
% Gln:
0
8
0
8
0
15
8
15
8
0
0
36
0
36
8
% Q
% Arg:
0
0
8
0
8
0
15
0
8
8
0
0
15
0
0
% R
% Ser:
15
8
8
0
0
50
0
8
8
0
8
15
8
8
8
% S
% Thr:
0
22
58
0
0
0
0
43
0
0
0
0
0
0
0
% T
% Val:
8
8
0
0
0
0
0
0
0
0
0
0
0
15
15
% V
% Trp:
0
8
0
0
22
0
0
0
0
0
43
0
8
0
0
% W
% Tyr:
43
0
0
0
8
8
0
0
0
0
15
15
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _