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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
METTL9
All Species:
21.82
Human Site:
S88
Identified Species:
36.92
UniProt:
Q9H1A3
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H1A3
NP_001070648.1
318
36536
S88
T
Q
I
F
L
N
N
S
I
E
K
S
G
W
L
Chimpanzee
Pan troglodytes
XP_001160038
277
32344
L55
S
I
E
K
S
G
W
L
F
I
Q
L
Y
H
S
Rhesus Macaque
Macaca mulatta
XP_001086688
323
36436
R84
A
S
V
W
L
A
Q
R
M
W
T
L
R
S
P
Dog
Lupus familis
XP_536936
277
32398
L55
S
I
E
K
S
G
W
L
F
I
Q
L
Y
H
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9EPL4
318
36407
S88
T
Q
I
F
L
N
N
S
I
E
K
S
G
W
L
Rat
Rattus norvegicus
NP_001156636
318
36423
S88
T
Q
I
F
L
N
N
S
I
E
K
S
G
W
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508171
357
41002
P100
R
R
C
P
R
S
C
P
P
F
Q
T
P
C
K
Chicken
Gallus gallus
Q5ZMH6
321
36990
S91
T
Q
I
F
L
N
N
S
I
E
K
S
G
W
L
Frog
Xenopus laevis
NP_001079600
315
36737
S86
T
Q
T
F
L
N
R
S
I
E
K
S
G
W
L
Zebra Danio
Brachydanio rerio
NP_001070810
234
26336
F12
V
F
I
F
W
L
L
F
Y
V
W
F
L
L
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611846
305
34724
S81
L
W
H
A
L
A
R
S
I
L
Q
F
F
M
T
Honey Bee
Apis mellifera
XP_623513
379
42710
S104
A
E
I
F
L
M
K
S
I
E
R
S
D
S
L
Nematode Worm
Caenorhab. elegans
NP_508880
311
35470
G81
T
D
I
N
G
M
T
G
F
G
N
M
F
L
F
Sea Urchin
Strong. purpuratus
XP_001188574
325
37619
W81
G
W
L
M
T
Q
M
W
H
S
L
A
K
A
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.9
78.9
83.6
N.A.
97.1
97.4
N.A.
61
86.9
72.9
39.9
N.A.
32.3
35.8
37.1
46.7
Protein Similarity:
100
84.9
79.2
84.2
N.A.
99.3
99
N.A.
64.4
90.6
83.6
49.6
N.A.
50
52.2
53.7
62.7
P-Site Identity:
100
0
6.6
0
N.A.
100
100
N.A.
0
100
86.6
13.3
N.A.
20
53.3
13.3
0
P-Site Similarity:
100
13.3
26.6
13.3
N.A.
100
100
N.A.
26.6
100
86.6
13.3
N.A.
26.6
66.6
13.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
0
0
8
0
15
0
0
0
0
0
8
0
8
8
% A
% Cys:
0
0
8
0
0
0
8
0
0
0
0
0
0
8
0
% C
% Asp:
0
8
0
0
0
0
0
0
0
0
0
0
8
0
0
% D
% Glu:
0
8
15
0
0
0
0
0
0
43
0
0
0
0
0
% E
% Phe:
0
8
0
50
0
0
0
8
22
8
0
15
15
0
8
% F
% Gly:
8
0
0
0
8
15
0
8
0
8
0
0
36
0
0
% G
% His:
0
0
8
0
0
0
0
0
8
0
0
0
0
15
0
% H
% Ile:
0
15
50
0
0
0
0
0
50
15
0
0
0
0
0
% I
% Lys:
0
0
0
15
0
0
8
0
0
0
36
0
8
0
8
% K
% Leu:
8
0
8
0
58
8
8
15
0
8
8
22
8
15
43
% L
% Met:
0
0
0
8
0
15
8
0
8
0
0
8
0
8
0
% M
% Asn:
0
0
0
8
0
36
29
0
0
0
8
0
0
0
0
% N
% Pro:
0
0
0
8
0
0
0
8
8
0
0
0
8
0
8
% P
% Gln:
0
36
0
0
0
8
8
0
0
0
29
0
0
0
0
% Q
% Arg:
8
8
0
0
8
0
15
8
0
0
8
0
8
0
0
% R
% Ser:
15
8
0
0
15
8
0
50
0
8
0
43
0
15
22
% S
% Thr:
43
0
8
0
8
0
8
0
0
0
8
8
0
0
8
% T
% Val:
8
0
8
0
0
0
0
0
0
8
0
0
0
0
0
% V
% Trp:
0
15
0
8
8
0
15
8
0
8
8
0
0
36
0
% W
% Tyr:
0
0
0
0
0
0
0
0
8
0
0
0
15
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _