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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: METTL9 All Species: 9.09
Human Site: S38 Identified Species: 15.38
UniProt: Q9H1A3 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H1A3 NP_001070648.1 318 36536 S38 S L Y V N M T S G P G G P A A
Chimpanzee Pan troglodytes XP_001160038 277 32344 D9 D R K T T S W D T K F Y E K W
Rhesus Macaque Macaca mulatta XP_001086688 323 36436 R36 T R W L E L G R W R L W P E A
Dog Lupus familis XP_536936 277 32398 D9 D R R I T S W D T K F Y E K W
Cat Felis silvestris
Mouse Mus musculus Q9EPL4 318 36407 S38 S L Y V N M T S G P G G P A A
Rat Rattus norvegicus NP_001156636 318 36423 S38 S L Y V N M T S G P G G P A A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508171 357 41002 A40 R G R H C Y R A G E G E R R A
Chicken Gallus gallus Q5ZMH6 321 36990 G44 S L Y A N M M G S H G P P A P
Frog Xenopus laevis NP_001079600 315 36737 L35 R S H L S R S L Y M N M M S H
Zebra Danio Brachydanio rerio NP_001070810 234 26336
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_611846 305 34724 L35 D T R K W Y C L N H E L P P R
Honey Bee Apis mellifera XP_623513 379 42710 R45 R P H G S L A R L L Y D K Q K
Nematode Worm Caenorhab. elegans NP_508880 311 35470 L35 Q N L F A A S L P D G E T Q Q
Sea Urchin Strong. purpuratus XP_001188574 325 37619 E35 L R K Y Y D V E K W Y R C D V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 83.9 78.9 83.6 N.A. 97.1 97.4 N.A. 61 86.9 72.9 39.9 N.A. 32.3 35.8 37.1 46.7
Protein Similarity: 100 84.9 79.2 84.2 N.A. 99.3 99 N.A. 64.4 90.6 83.6 49.6 N.A. 50 52.2 53.7 62.7
P-Site Identity: 100 0 13.3 0 N.A. 100 100 N.A. 20 53.3 0 0 N.A. 6.6 0 6.6 0
P-Site Similarity: 100 0 40 6.6 N.A. 100 100 N.A. 26.6 53.3 33.3 0 N.A. 6.6 20 13.3 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 8 8 8 8 0 0 0 0 0 29 36 % A
% Cys: 0 0 0 0 8 0 8 0 0 0 0 0 8 0 0 % C
% Asp: 22 0 0 0 0 8 0 15 0 8 0 8 0 8 0 % D
% Glu: 0 0 0 0 8 0 0 8 0 8 8 15 15 8 0 % E
% Phe: 0 0 0 8 0 0 0 0 0 0 15 0 0 0 0 % F
% Gly: 0 8 0 8 0 0 8 8 29 0 43 22 0 0 0 % G
% His: 0 0 15 8 0 0 0 0 0 15 0 0 0 0 8 % H
% Ile: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 15 8 0 0 0 0 8 15 0 0 8 15 8 % K
% Leu: 8 29 8 15 0 15 0 22 8 8 8 8 0 0 0 % L
% Met: 0 0 0 0 0 29 8 0 0 8 0 8 8 0 0 % M
% Asn: 0 8 0 0 29 0 0 0 8 0 8 0 0 0 0 % N
% Pro: 0 8 0 0 0 0 0 0 8 22 0 8 43 8 8 % P
% Gln: 8 0 0 0 0 0 0 0 0 0 0 0 0 15 8 % Q
% Arg: 22 29 22 0 0 8 8 15 0 8 0 8 8 8 8 % R
% Ser: 29 8 0 0 15 15 15 22 8 0 0 0 0 8 0 % S
% Thr: 8 8 0 8 15 0 22 0 15 0 0 0 8 0 0 % T
% Val: 0 0 0 22 0 0 8 0 0 0 0 0 0 0 8 % V
% Trp: 0 0 8 0 8 0 15 0 8 8 0 8 0 0 15 % W
% Tyr: 0 0 29 8 8 15 0 0 8 0 15 15 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _