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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NT5C3
All Species:
30
Human Site:
Y315
Identified Species:
60
UniProt:
Q9H0P0
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H0P0
NP_001002009.1
336
37948
Y315
L
E
K
Y
M
D
S
Y
D
I
V
L
V
Q
D
Chimpanzee
Pan troglodytes
XP_001167622
331
37387
Y310
L
E
K
Y
M
D
S
Y
D
I
V
L
V
Q
D
Rhesus Macaque
Macaca mulatta
XP_001107648
336
37930
Y315
L
E
K
Y
M
N
S
Y
D
I
V
L
V
Q
D
Dog
Lupus familis
XP_852141
331
37476
Y310
L
E
K
Y
M
D
S
Y
D
I
V
L
V
K
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9D020
331
37234
Y310
L
E
K
Y
M
D
S
Y
D
I
V
L
V
K
E
Rat
Rattus norvegicus
Q6AYP7
292
33670
V272
E
K
D
E
T
L
D
V
V
N
G
L
L
Q
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506646
336
37870
Y315
L
E
K
Y
K
D
L
Y
D
I
V
L
V
K
E
Chicken
Gallus gallus
Q5ZID6
331
37352
Y310
L
E
K
Y
M
D
S
Y
D
I
V
L
V
K
D
Frog
Xenopus laevis
Q7ZWS2
290
33482
L270
L
Q
S
Y
D
I
V
L
L
R
D
E
T
L
D
Zebra Danio
Brachydanio rerio
Q7SYN4
286
32918
N266
E
K
Y
M
D
S
Y
N
I
V
L
A
R
D
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09315
376
42128
Y352
L
Q
H
Y
E
E
V
Y
D
I
V
L
I
H
D
Sea Urchin
Strong. purpuratus
XP_781890
284
31941
D264
E
S
Y
K
D
S
F
D
I
V
L
I
S
D
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
99.4
91
N.A.
92.2
48.8
N.A.
88.6
86
50
68.7
N.A.
N.A.
N.A.
31.6
41.9
Protein Similarity:
100
98.5
100
96.1
N.A.
96.1
66.6
N.A.
94.3
92.2
67.8
76.7
N.A.
N.A.
N.A.
52.3
61
P-Site Identity:
100
100
93.3
93.3
N.A.
86.6
13.3
N.A.
73.3
93.3
20
0
N.A.
N.A.
N.A.
53.3
0
P-Site Similarity:
100
100
100
100
N.A.
100
26.6
N.A.
86.6
100
26.6
26.6
N.A.
N.A.
N.A.
73.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
9
0
25
50
9
9
67
0
9
0
0
17
59
% D
% Glu:
25
59
0
9
9
9
0
0
0
0
0
9
0
0
34
% E
% Phe:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% G
% His:
0
0
9
0
0
0
0
0
0
0
0
0
0
9
9
% H
% Ile:
0
0
0
0
0
9
0
0
17
67
0
9
9
0
0
% I
% Lys:
0
17
59
9
9
0
0
0
0
0
0
0
0
34
0
% K
% Leu:
75
0
0
0
0
9
9
9
9
0
17
75
9
9
0
% L
% Met:
0
0
0
9
50
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
9
0
9
0
9
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
17
0
0
0
0
0
0
0
0
0
0
0
34
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
9
0
0
9
0
0
% R
% Ser:
0
9
9
0
0
17
50
0
0
0
0
0
9
0
0
% S
% Thr:
0
0
0
0
9
0
0
0
0
0
0
0
9
0
0
% T
% Val:
0
0
0
0
0
0
17
9
9
17
67
0
59
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
17
75
0
0
9
67
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _