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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NT5C3
All Species:
29.7
Human Site:
T260
Identified Species:
59.39
UniProt:
Q9H0P0
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H0P0
NP_001002009.1
336
37948
T260
H
D
G
A
L
R
N
T
E
Y
F
N
Q
L
K
Chimpanzee
Pan troglodytes
XP_001167622
331
37387
T255
H
D
G
A
L
R
N
T
E
Y
F
N
Q
L
K
Rhesus Macaque
Macaca mulatta
XP_001107648
336
37930
T260
H
D
G
A
L
R
N
T
E
Y
F
N
Q
L
K
Dog
Lupus familis
XP_852141
331
37476
T255
H
D
G
A
L
K
N
T
E
Y
F
N
R
L
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9D020
331
37234
T255
H
D
G
A
L
K
N
T
D
Y
F
S
Q
L
K
Rat
Rattus norvegicus
Q6AYP7
292
33670
S223
N
I
I
L
L
G
D
S
I
G
D
L
T
M
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506646
336
37870
T260
H
D
G
A
L
K
R
T
E
Y
F
K
N
L
K
Chicken
Gallus gallus
Q5ZID6
331
37352
T255
H
D
G
A
L
K
N
T
E
Y
F
K
Q
L
K
Frog
Xenopus laevis
Q7ZWS2
290
33482
T221
F
K
E
I
S
H
R
T
N
I
L
L
L
G
D
Zebra Danio
Brachydanio rerio
Q7SYN4
286
32918
K217
T
E
Y
F
K
Q
L
K
D
N
G
N
I
I
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09315
376
42128
T295
S
S
V
I
Q
K
E
T
S
F
F
H
D
I
A
Sea Urchin
Strong. purpuratus
XP_781890
284
31941
K215
P
E
Y
F
E
R
H
K
H
R
T
N
V
I
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
99.4
91
N.A.
92.2
48.8
N.A.
88.6
86
50
68.7
N.A.
N.A.
N.A.
31.6
41.9
Protein Similarity:
100
98.5
100
96.1
N.A.
96.1
66.6
N.A.
94.3
92.2
67.8
76.7
N.A.
N.A.
N.A.
52.3
61
P-Site Identity:
100
100
100
86.6
N.A.
80
6.6
N.A.
73.3
86.6
6.6
6.6
N.A.
N.A.
N.A.
13.3
13.3
P-Site Similarity:
100
100
100
100
N.A.
100
33.3
N.A.
80
93.3
6.6
33.3
N.A.
N.A.
N.A.
40
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
59
0
0
0
0
0
0
0
0
0
0
17
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
59
0
0
0
0
9
0
17
0
9
0
9
0
9
% D
% Glu:
0
17
9
0
9
0
9
0
50
0
0
0
0
0
0
% E
% Phe:
9
0
0
17
0
0
0
0
0
9
67
0
0
0
0
% F
% Gly:
0
0
59
0
0
9
0
0
0
9
9
0
0
9
0
% G
% His:
59
0
0
0
0
9
9
0
9
0
0
9
0
0
0
% H
% Ile:
0
9
9
17
0
0
0
0
9
9
0
0
9
25
0
% I
% Lys:
0
9
0
0
9
42
0
17
0
0
0
17
0
0
59
% K
% Leu:
0
0
0
9
67
0
9
0
0
0
9
17
9
59
17
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% M
% Asn:
9
0
0
0
0
0
50
0
9
9
0
50
9
0
0
% N
% Pro:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
9
9
0
0
0
0
0
0
42
0
0
% Q
% Arg:
0
0
0
0
0
34
17
0
0
9
0
0
9
0
0
% R
% Ser:
9
9
0
0
9
0
0
9
9
0
0
9
0
0
0
% S
% Thr:
9
0
0
0
0
0
0
75
0
0
9
0
9
0
0
% T
% Val:
0
0
9
0
0
0
0
0
0
0
0
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
17
0
0
0
0
0
0
59
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _