KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NT5C3
All Species:
10
Human Site:
S59
Identified Species:
20
UniProt:
Q9H0P0
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H0P0
NP_001002009.1
336
37948
S59
M
P
E
F
Q
K
S
S
V
R
I
K
N
P
T
Chimpanzee
Pan troglodytes
XP_001167622
331
37387
N59
K
S
S
V
R
I
K
N
P
T
R
V
E
E
I
Rhesus Macaque
Macaca mulatta
XP_001107648
336
37930
S59
M
P
E
F
Q
K
S
S
V
R
I
K
N
P
T
Dog
Lupus familis
XP_852141
331
37476
N59
R
S
S
V
R
I
K
N
P
A
R
V
E
E
I
Cat
Felis silvestris
Mouse
Mus musculus
Q9D020
331
37234
N59
K
S
S
V
R
I
K
N
P
T
R
V
E
E
I
Rat
Rattus norvegicus
Q6AYP7
292
33670
N44
T
L
S
R
F
A
Y
N
G
Q
R
C
P
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506646
336
37870
S59
M
P
E
F
Q
K
S
S
V
H
I
K
N
P
T
Chicken
Gallus gallus
Q5ZID6
331
37352
D59
K
K
T
V
H
I
K
D
P
G
R
V
E
E
I
Frog
Xenopus laevis
Q7ZWS2
290
33482
T43
I
I
S
D
F
D
M
T
L
S
R
F
S
R
N
Zebra Danio
Brachydanio rerio
Q7SYN4
286
32918
F39
K
L
Q
I
I
T
D
F
D
M
T
L
S
R
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09315
376
42128
P79
L
K
K
T
D
V
V
P
L
L
M
N
Y
L
L
Sea Urchin
Strong. purpuratus
XP_781890
284
31941
F37
N
Y
M
V
V
S
D
F
D
R
T
I
T
R
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
99.4
91
N.A.
92.2
48.8
N.A.
88.6
86
50
68.7
N.A.
N.A.
N.A.
31.6
41.9
Protein Similarity:
100
98.5
100
96.1
N.A.
96.1
66.6
N.A.
94.3
92.2
67.8
76.7
N.A.
N.A.
N.A.
52.3
61
P-Site Identity:
100
0
100
0
N.A.
0
0
N.A.
93.3
0
0
0
N.A.
N.A.
N.A.
0
6.6
P-Site Similarity:
100
13.3
100
13.3
N.A.
13.3
20
N.A.
93.3
0
26.6
13.3
N.A.
N.A.
N.A.
26.6
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
9
0
0
0
9
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% C
% Asp:
0
0
0
9
9
9
17
9
17
0
0
0
0
0
0
% D
% Glu:
0
0
25
0
0
0
0
0
0
0
0
0
34
34
0
% E
% Phe:
0
0
0
25
17
0
0
17
0
0
0
9
0
0
17
% F
% Gly:
0
0
0
0
0
0
0
0
9
9
0
0
0
0
0
% G
% His:
0
0
0
0
9
0
0
0
0
9
0
0
0
0
0
% H
% Ile:
9
9
0
9
9
34
0
0
0
0
25
9
0
0
34
% I
% Lys:
34
17
9
0
0
25
34
0
0
0
0
25
0
0
0
% K
% Leu:
9
17
0
0
0
0
0
0
17
9
0
9
0
9
9
% L
% Met:
25
0
9
0
0
0
9
0
0
9
9
0
0
0
0
% M
% Asn:
9
0
0
0
0
0
0
34
0
0
0
9
25
0
9
% N
% Pro:
0
25
0
0
0
0
0
9
34
0
0
0
9
25
0
% P
% Gln:
0
0
9
0
25
0
0
0
0
9
0
0
0
0
0
% Q
% Arg:
9
0
0
9
25
0
0
0
0
25
50
0
0
25
0
% R
% Ser:
0
25
42
0
0
9
25
25
0
9
0
0
17
9
9
% S
% Thr:
9
0
9
9
0
9
0
9
0
17
17
0
9
0
25
% T
% Val:
0
0
0
42
9
9
9
0
25
0
0
34
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
0
0
0
0
9
0
0
0
0
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _