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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NT5C3
All Species:
29.7
Human Site:
S228
Identified Species:
59.39
UniProt:
Q9H0P0
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H0P0
NP_001002009.1
336
37948
S228
H
P
N
V
K
V
V
S
N
F
M
D
F
D
E
Chimpanzee
Pan troglodytes
XP_001167622
331
37387
S223
H
P
N
V
K
V
V
S
N
F
M
D
F
D
E
Rhesus Macaque
Macaca mulatta
XP_001107648
336
37930
S228
H
P
N
V
K
V
V
S
N
F
M
D
F
D
E
Dog
Lupus familis
XP_852141
331
37476
S223
H
P
N
I
T
V
V
S
N
F
M
D
F
D
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9D020
331
37234
S223
H
S
N
V
K
V
V
S
N
F
M
D
F
D
E
Rat
Rattus norvegicus
Q6AYP7
292
33670
S200
H
T
Y
N
K
N
S
S
V
C
E
N
S
S
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506646
336
37870
S228
H
S
N
I
K
V
V
S
N
F
M
D
F
D
D
Chicken
Gallus gallus
Q5ZID6
331
37352
S223
H
S
N
V
K
V
V
S
N
F
M
D
F
D
E
Frog
Xenopus laevis
Q7ZWS2
290
33482
I198
T
G
F
K
G
D
L
I
H
T
Y
N
K
N
S
Zebra Danio
Brachydanio rerio
Q7SYN4
286
32918
G194
G
V
L
K
G
F
K
G
E
L
I
H
V
Y
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09315
376
42128
S262
P
R
N
T
H
F
I
S
N
M
I
L
F
D
E
Sea Urchin
Strong. purpuratus
XP_781890
284
31941
G192
D
N
L
V
G
F
K
G
E
M
I
H
T
Y
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
99.4
91
N.A.
92.2
48.8
N.A.
88.6
86
50
68.7
N.A.
N.A.
N.A.
31.6
41.9
Protein Similarity:
100
98.5
100
96.1
N.A.
96.1
66.6
N.A.
94.3
92.2
67.8
76.7
N.A.
N.A.
N.A.
52.3
61
P-Site Identity:
100
100
100
80
N.A.
93.3
20
N.A.
80
93.3
0
0
N.A.
N.A.
N.A.
40
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
26.6
N.A.
93.3
93.3
26.6
6.6
N.A.
N.A.
N.A.
53.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% C
% Asp:
9
0
0
0
0
9
0
0
0
0
0
59
0
67
17
% D
% Glu:
0
0
0
0
0
0
0
0
17
0
9
0
0
0
50
% E
% Phe:
0
0
9
0
0
25
0
0
0
59
0
0
67
0
0
% F
% Gly:
9
9
0
0
25
0
0
17
0
0
0
0
0
0
0
% G
% His:
67
0
0
0
9
0
0
0
9
0
0
17
0
0
0
% H
% Ile:
0
0
0
17
0
0
9
9
0
0
25
0
0
0
0
% I
% Lys:
0
0
0
17
59
0
17
0
0
0
0
0
9
0
0
% K
% Leu:
0
0
17
0
0
0
9
0
0
9
0
9
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
17
59
0
0
0
0
% M
% Asn:
0
9
67
9
0
9
0
0
67
0
0
17
0
9
17
% N
% Pro:
9
34
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
25
0
0
0
0
9
75
0
0
0
0
9
9
9
% S
% Thr:
9
9
0
9
9
0
0
0
0
9
0
0
9
0
0
% T
% Val:
0
9
0
50
0
59
59
0
9
0
0
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
9
0
0
0
0
0
0
0
9
0
0
17
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _