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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RACGAP1
All Species:
21.52
Human Site:
T249
Identified Species:
39.44
UniProt:
Q9H0H5
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.42
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H0H5
NP_001119575.1
632
71027
T249
W
T
R
S
R
R
K
T
G
T
L
Q
P
W
N
Chimpanzee
Pan troglodytes
XP_001156917
632
70976
T249
W
T
R
S
R
R
K
T
G
T
L
Q
P
W
N
Rhesus Macaque
Macaca mulatta
XP_001110799
632
71000
T249
W
T
R
S
R
R
K
T
G
T
L
Q
P
W
N
Dog
Lupus familis
XP_543675
632
70923
T249
W
M
R
S
R
R
K
T
G
T
L
Q
P
W
N
Cat
Felis silvestris
Mouse
Mus musculus
Q9WVM1
628
70140
S250
W
T
R
S
R
G
K
S
G
P
L
Q
P
V
N
Rat
Rattus norvegicus
NP_001101582
626
69901
K248
C
W
T
R
S
R
G
K
S
G
P
L
Q
P
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515108
632
70770
S249
W
T
R
S
R
R
K
S
G
A
L
Q
P
W
S
Chicken
Gallus gallus
Q5ZMW5
760
86506
F280
Y
V
Q
E
K
R
H
F
G
T
S
W
V
K
H
Frog
Xenopus laevis
NP_001084820
629
70764
R248
Y
Y
N
T
R
G
R
R
T
G
T
L
Q
P
W
Zebra Danio
Brachydanio rerio
NP_955925
654
73180
T272
S
A
A
V
E
W
D
T
V
D
T
D
S
V
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P40809
384
44198
R8
M
I
S
G
S
G
S
R
T
P
S
N
R
L
Y
Honey Bee
Apis mellifera
XP_393627
598
66406
K210
K
R
R
S
G
T
Q
K
T
T
E
L
T
S
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783360
661
74293
K238
I
A
T
T
N
V
E
K
N
G
R
Y
R
R
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
98.8
96
N.A.
84.6
85.1
N.A.
87.5
21.5
76.9
65.1
N.A.
25.9
38.9
N.A.
43.8
Protein Similarity:
100
100
99.6
98.2
N.A.
91.7
92
N.A.
94.7
37.6
89
81.1
N.A.
38.1
55.2
N.A.
61.7
P-Site Identity:
100
100
100
93.3
N.A.
73.3
6.6
N.A.
80
20
6.6
6.6
N.A.
0
20
N.A.
0
P-Site Similarity:
100
100
100
93.3
N.A.
80
6.6
N.A.
93.3
46.6
26.6
6.6
N.A.
0
33.3
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
16
8
0
0
0
0
0
0
8
0
0
0
0
0
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
8
0
0
8
0
8
0
0
0
% D
% Glu:
0
0
0
8
8
0
8
0
0
0
8
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
8
8
24
8
0
54
24
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
8
% H
% Ile:
8
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
8
0
0
0
8
0
47
24
0
0
0
0
0
8
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
47
24
0
8
0
% L
% Met:
8
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
8
0
0
0
8
0
0
8
0
0
39
% N
% Pro:
0
0
0
0
0
0
0
0
0
16
8
0
47
16
0
% P
% Gln:
0
0
8
0
0
0
8
0
0
0
0
47
16
0
8
% Q
% Arg:
0
8
54
8
54
54
8
16
0
0
8
0
16
8
0
% R
% Ser:
8
0
8
54
16
0
8
16
8
0
16
0
8
8
24
% S
% Thr:
0
39
16
16
0
8
0
39
24
47
16
0
8
0
0
% T
% Val:
0
8
0
8
0
8
0
0
8
0
0
0
8
16
8
% V
% Trp:
47
8
0
0
0
8
0
0
0
0
0
8
0
39
8
% W
% Tyr:
16
8
0
0
0
0
0
0
0
0
0
8
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _