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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RACGAP1
All Species:
23.94
Human Site:
S185
Identified Species:
43.89
UniProt:
Q9H0H5
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H0H5
NP_001119575.1
632
71027
S185
K
K
R
E
K
R
R
S
T
S
R
Q
F
V
D
Chimpanzee
Pan troglodytes
XP_001156917
632
70976
S185
K
K
R
E
K
R
R
S
T
S
R
Q
F
V
D
Rhesus Macaque
Macaca mulatta
XP_001110799
632
71000
S185
K
K
R
E
K
R
R
S
S
S
R
Q
F
V
D
Dog
Lupus familis
XP_543675
632
70923
S185
K
K
R
E
K
R
R
S
S
S
R
Q
F
I
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9WVM1
628
70140
S186
K
K
R
E
K
R
R
S
N
S
R
Q
F
I
D
Rat
Rattus norvegicus
NP_001101582
626
69901
R184
M
K
K
R
E
K
R
R
S
S
S
R
Q
F
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515108
632
70770
S185
K
K
R
E
K
R
R
S
N
S
R
Q
F
I
E
Chicken
Gallus gallus
Q5ZMW5
760
86506
E216
T
F
Y
H
H
G
Y
E
L
A
K
D
F
S
D
Frog
Xenopus laevis
NP_001084820
629
70764
R184
K
L
K
K
R
E
K
R
R
S
S
R
Q
H
T
Zebra Danio
Brachydanio rerio
NP_955925
654
73180
T208
R
S
R
S
T
G
R
T
S
E
K
G
N
E
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P40809
384
44198
Honey Bee
Apis mellifera
XP_393627
598
66406
N146
H
I
K
D
V
H
Q
N
E
K
L
N
T
I
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783360
661
74293
L174
L
D
H
T
E
E
E
L
D
V
S
V
L
R
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
98.8
96
N.A.
84.6
85.1
N.A.
87.5
21.5
76.9
65.1
N.A.
25.9
38.9
N.A.
43.8
Protein Similarity:
100
100
99.6
98.2
N.A.
91.7
92
N.A.
94.7
37.6
89
81.1
N.A.
38.1
55.2
N.A.
61.7
P-Site Identity:
100
100
93.3
86.6
N.A.
86.6
20
N.A.
80
13.3
13.3
13.3
N.A.
0
0
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
93.3
53.3
N.A.
93.3
26.6
46.6
40
N.A.
0
33.3
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
8
0
0
0
0
8
0
0
8
0
0
54
% D
% Glu:
0
0
0
47
16
16
8
8
8
8
0
0
0
8
8
% E
% Phe:
0
8
0
0
0
0
0
0
0
0
0
0
54
8
0
% F
% Gly:
0
0
0
0
0
16
0
0
0
0
0
8
0
0
0
% G
% His:
8
0
8
8
8
8
0
0
0
0
0
0
0
8
0
% H
% Ile:
0
8
0
0
0
0
0
0
0
0
0
0
0
31
8
% I
% Lys:
54
54
24
8
47
8
8
0
0
8
16
0
0
0
0
% K
% Leu:
8
8
0
0
0
0
0
8
8
0
8
0
8
0
0
% L
% Met:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
8
16
0
0
8
8
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
8
0
0
0
0
47
16
0
0
% Q
% Arg:
8
0
54
8
8
47
62
16
8
0
47
16
0
8
0
% R
% Ser:
0
8
0
8
0
0
0
47
31
62
24
0
0
8
8
% S
% Thr:
8
0
0
8
8
0
0
8
16
0
0
0
8
0
8
% T
% Val:
0
0
0
0
8
0
0
0
0
8
0
8
0
24
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
8
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _