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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ILKAP All Species: 26.06
Human Site: S59 Identified Species: 40.95
UniProt: Q9H0C8 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H0C8 NP_110395.1 392 42907 S59 P P A S S G D S G S L A T S I
Chimpanzee Pan troglodytes XP_001152781 553 60157 S222 P P A S S G D S G S L A T S I
Rhesus Macaque Macaca mulatta XP_001094705 590 64766 S259 P P A S S G D S G S L A P S I
Dog Lupus familis XP_543305 401 43921 S59 P P A S S G D S G P L D T S M
Cat Felis silvestris
Mouse Mus musculus Q8R0F6 392 42756 S59 P P A A S G N S G S L A T S G
Rat Rattus norvegicus Q9Z1Z6 392 42726 S59 P P A G S G N S G S L A T S G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513557 590 63726 S102 P P A S S G N S G S Q A T Q T
Chicken Gallus gallus XP_422661 389 42657 A56 P P A S S S D A A S S A P E Q
Frog Xenopus laevis NP_001086890 344 37998 D40 K R K A E T A D S D S C E G Q
Zebra Danio Brachydanio rerio NP_001082973 129 14081
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_496370 242 26827
Sea Urchin Strong. purpuratus XP_001180671 354 39861 T47 Q E G G E E E T G N L K R K S
Poplar Tree Populus trichocarpa XP_002321498 266 28901
Maize Zea mays NP_001130289 360 39005 C49 D A E A R R T C Q K E S E A P
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LMT1 351 38467 E46 E E V S G G G E A V A A V G N
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 70.3 65 94.2 N.A. 95.1 95.1 N.A. 60.1 84.1 58.1 23.7 N.A. N.A. N.A. 28.8 47.7
Protein Similarity: 100 70.5 65.2 95.2 N.A. 97.6 96.9 N.A. 62.8 88.5 72.6 29.3 N.A. N.A. N.A. 42.5 65
P-Site Identity: 100 100 93.3 80 N.A. 80 80 N.A. 73.3 53.3 0 0 N.A. N.A. N.A. 0 13.3
P-Site Similarity: 100 100 93.3 86.6 N.A. 93.3 86.6 N.A. 80 60 6.6 0 N.A. N.A. N.A. 0 33.3
Percent
Protein Identity: 26.7 33.1 N.A. 32.4 N.A. N.A.
Protein Similarity: 38.2 53.8 N.A. 52.8 N.A. N.A.
P-Site Identity: 0 0 N.A. 20 N.A. N.A.
P-Site Similarity: 0 20 N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 54 20 0 0 7 7 14 0 7 54 0 7 0 % A
% Cys: 0 0 0 0 0 0 0 7 0 0 0 7 0 0 0 % C
% Asp: 7 0 0 0 0 0 34 7 0 7 0 7 0 0 0 % D
% Glu: 7 14 7 0 14 7 7 7 0 0 7 0 14 7 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 7 14 7 54 7 0 54 0 0 0 0 14 14 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 20 % I
% Lys: 7 0 7 0 0 0 0 0 0 7 0 7 0 7 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 47 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % M
% Asn: 0 0 0 0 0 0 20 0 0 7 0 0 0 0 7 % N
% Pro: 54 54 0 0 0 0 0 0 0 7 0 0 14 0 7 % P
% Gln: 7 0 0 0 0 0 0 0 7 0 7 0 0 7 14 % Q
% Arg: 0 7 0 0 7 7 0 0 0 0 0 0 7 0 0 % R
% Ser: 0 0 0 47 54 7 0 47 7 47 14 7 0 40 7 % S
% Thr: 0 0 0 0 0 7 7 7 0 0 0 0 40 0 7 % T
% Val: 0 0 7 0 0 0 0 0 0 7 0 0 7 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _