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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TMEM117 All Species: 17.27
Human Site: Y374 Identified Species: 63.33
UniProt: Q9H0C3 Number Species: 6
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H0C3 NP_115632.1 514 60185 Y374 N P R T N K T Y V E G D M F L
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001092306 514 60138 Y374 N P Q T N K T Y V E G D M F L
Dog Lupus familis XP_852094 347 40667 N223 E W R S N H T N P Q T N K T Y
Cat Felis silvestris
Mouse Mus musculus Q8BH18 514 60338 Y374 N P Q T N K T Y V E G D M F L
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_416041 558 64868 Y420 N P L T N R T Y A E G D M F L
Frog Xenopus laevis NP_001090438 504 58917 Y373 D P Y T N R S Y V E G D M F L
Zebra Danio Brachydanio rerio Q7ZVW1 401 47554 Q277 F D L L I V M Q D W E F P H F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 99.8 65.9 N.A. 95.9 N.A. N.A. N.A. 78.3 74.9 57.2 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 N.A. 100 66.3 N.A. 97 N.A. N.A. N.A. 83.5 85.5 66.5 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 N.A. 93.3 20 N.A. 93.3 N.A. N.A. N.A. 80 73.3 0 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 N.A. 100 40 N.A. 100 N.A. N.A. N.A. 86.6 93.3 0 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 15 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 15 15 0 0 0 0 0 0 15 0 0 72 0 0 0 % D
% Glu: 15 0 0 0 0 0 0 0 0 72 15 0 0 0 0 % E
% Phe: 15 0 0 0 0 0 0 0 0 0 0 15 0 72 15 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 72 0 0 0 0 % G
% His: 0 0 0 0 0 15 0 0 0 0 0 0 0 15 0 % H
% Ile: 0 0 0 0 15 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 43 0 0 0 0 0 0 15 0 0 % K
% Leu: 0 0 29 15 0 0 0 0 0 0 0 0 0 0 72 % L
% Met: 0 0 0 0 0 0 15 0 0 0 0 0 72 0 0 % M
% Asn: 58 0 0 0 86 0 0 15 0 0 0 15 0 0 0 % N
% Pro: 0 72 0 0 0 0 0 0 15 0 0 0 15 0 0 % P
% Gln: 0 0 29 0 0 0 0 15 0 15 0 0 0 0 0 % Q
% Arg: 0 0 29 0 0 29 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 15 0 0 15 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 72 0 0 72 0 0 0 15 0 0 15 0 % T
% Val: 0 0 0 0 0 15 0 0 58 0 0 0 0 0 0 % V
% Trp: 0 15 0 0 0 0 0 0 0 15 0 0 0 0 0 % W
% Tyr: 0 0 15 0 0 0 0 72 0 0 0 0 0 0 15 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _