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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
COMMD4
All Species:
29.09
Human Site:
S125
Identified Species:
53.33
UniProt:
Q9H0A8
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H0A8
NP_060298.2
199
21764
S125
Q
K
H
L
R
V
C
S
L
R
M
N
R
L
A
Chimpanzee
Pan troglodytes
XP_510680
409
44350
S335
Q
K
H
L
R
V
C
S
L
R
M
N
R
L
A
Rhesus Macaque
Macaca mulatta
XP_001101270
200
21927
S124
S
V
D
G
E
S
L
S
S
E
L
Q
Q
L
G
Dog
Lupus familis
XP_853327
199
21783
S125
Q
E
H
L
R
A
C
S
L
R
V
N
R
L
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9CQ02
199
21842
S125
Q
E
H
L
R
A
C
S
L
R
V
N
R
L
A
Rat
Rattus norvegicus
NP_001102232
177
19467
R108
A
C
S
L
R
V
N
R
L
A
S
V
G
W
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518553
198
21716
S124
Q
D
S
L
R
A
C
S
L
R
L
N
R
L
E
Chicken
Gallus gallus
XP_001233363
199
22075
S125
Q
D
S
L
R
A
G
S
L
R
L
S
R
L
D
Frog
Xenopus laevis
NP_001089048
197
22070
S125
Q
E
T
L
R
E
S
S
L
R
L
T
R
M
S
Zebra Danio
Brachydanio rerio
NP_001070206
134
15049
I65
A
K
F
D
S
G
D
I
K
A
C
I
G
V
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001034012
198
22035
S123
R
Q
T
L
I
N
K
S
F
R
I
N
E
L
T
Honey Bee
Apis mellifera
XP_393404
188
20764
P115
R
L
H
T
D
Y
C
P
Q
I
T
A
T
L
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785030
205
23099
S131
Q
E
S
F
R
S
R
S
L
R
L
S
K
F
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
48.4
69
93.9
N.A.
90.9
79.4
N.A.
81.4
72.8
65.3
49.2
N.A.
34.6
40.7
N.A.
56.5
Protein Similarity:
100
48.6
72.5
97.9
N.A.
95.9
84.4
N.A.
89.9
82.9
83.9
59.2
N.A.
55.2
62.3
N.A.
75.6
P-Site Identity:
100
100
13.3
80
N.A.
80
26.6
N.A.
66.6
53.3
46.6
6.6
N.A.
33.3
20
N.A.
33.3
P-Site Similarity:
100
100
26.6
93.3
N.A.
93.3
26.6
N.A.
73.3
66.6
73.3
13.3
N.A.
53.3
33.3
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
0
0
0
0
31
0
0
0
16
0
8
0
0
31
% A
% Cys:
0
8
0
0
0
0
47
0
0
0
8
0
0
0
0
% C
% Asp:
0
16
8
8
8
0
8
0
0
0
0
0
0
0
16
% D
% Glu:
0
31
0
0
8
8
0
0
0
8
0
0
8
0
8
% E
% Phe:
0
0
8
8
0
0
0
0
8
0
0
0
0
8
0
% F
% Gly:
0
0
0
8
0
8
8
0
0
0
0
0
16
0
8
% G
% His:
0
0
39
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
8
0
0
8
0
8
8
8
0
0
0
% I
% Lys:
0
24
0
0
0
0
8
0
8
0
0
0
8
0
0
% K
% Leu:
0
8
0
70
0
0
8
0
70
0
39
0
0
70
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
16
0
0
8
0
% M
% Asn:
0
0
0
0
0
8
8
0
0
0
0
47
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% P
% Gln:
62
8
0
0
0
0
0
0
8
0
0
8
8
0
0
% Q
% Arg:
16
0
0
0
70
0
8
8
0
70
0
0
54
0
8
% R
% Ser:
8
0
31
0
8
16
8
77
8
0
8
16
0
0
16
% S
% Thr:
0
0
16
8
0
0
0
0
0
0
8
8
8
0
8
% T
% Val:
0
8
0
0
0
24
0
0
0
0
16
8
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% W
% Tyr:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _