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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
UBE2O
All Species:
21.82
Human Site:
S721
Identified Species:
40
UniProt:
Q9C0C9
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9C0C9
NP_071349.3
1292
141293
S721
I
E
E
S
D
Y
D
S
V
E
G
S
T
S
G
Chimpanzee
Pan troglodytes
XP_001139963
1392
151306
T717
A
A
D
D
T
D
D
T
S
S
V
T
S
S
A
Rhesus Macaque
Macaca mulatta
XP_001099166
1374
150150
S802
I
E
E
S
D
Y
D
S
V
E
G
S
T
S
G
Dog
Lupus familis
XP_540449
1328
145864
S756
I
E
E
S
D
Y
D
S
V
E
G
S
T
S
G
Cat
Felis silvestris
Mouse
Mus musculus
Q6ZPJ3
1288
140799
S716
I
E
E
S
D
Y
D
S
V
E
G
S
S
S
G
Rat
Rattus norvegicus
XP_221132
1291
140971
S719
I
E
E
S
D
Y
D
S
V
E
G
S
T
S
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507962
1095
118343
C584
G
D
H
I
G
R
T
C
V
V
K
W
F
K
L
Chicken
Gallus gallus
XP_415619
1288
141077
V722
E
E
S
D
Y
D
S
V
D
G
S
T
S
G
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_692656
586
64314
A75
S
I
S
S
S
T
T
A
T
T
S
D
E
K
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651170
1398
156627
G722
E
Q
D
Q
D
V
Y
G
S
D
G
S
E
D
S
Honey Bee
Apis mellifera
XP_001120701
1287
145895
S760
D
K
N
S
T
E
N
S
N
N
I
V
Q
S
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002313703
1079
118536
V568
Y
S
Y
G
D
V
V
V
R
L
S
P
V
T
V
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9ZVX1
1102
122164
Q590
S
F
E
E
A
T
Q
Q
D
N
G
Y
Q
D
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
82.4
93.3
90.9
N.A.
94.1
94.2
N.A.
69.1
77.6
N.A.
28
N.A.
21.8
20.7
N.A.
N.A.
Protein Similarity:
100
82.9
93.6
92.9
N.A.
96.1
96
N.A.
74.3
83.9
N.A.
35.2
N.A.
39.9
35.6
N.A.
N.A.
P-Site Identity:
100
13.3
100
100
N.A.
93.3
100
N.A.
6.6
6.6
N.A.
6.6
N.A.
20
26.6
N.A.
N.A.
P-Site Similarity:
100
40
100
100
N.A.
100
100
N.A.
13.3
20
N.A.
13.3
N.A.
40
40
N.A.
N.A.
Percent
Protein Identity:
25.7
N.A.
N.A.
23.3
N.A.
N.A.
Protein Similarity:
41.8
N.A.
N.A.
39.9
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
0
8
0
0
8
0
0
0
0
0
0
16
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% C
% Asp:
8
8
16
16
54
16
47
0
16
8
0
8
0
16
0
% D
% Glu:
16
47
47
8
0
8
0
0
0
39
0
0
16
0
0
% E
% Phe:
0
8
0
0
0
0
0
0
0
0
0
0
8
0
0
% F
% Gly:
8
0
0
8
8
0
0
8
0
8
54
0
0
8
47
% G
% His:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
39
8
0
8
0
0
0
0
0
0
8
0
0
0
0
% I
% Lys:
0
8
0
0
0
0
0
0
0
0
8
0
0
16
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
0
0
8
0
8
16
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% P
% Gln:
0
8
0
8
0
0
8
8
0
0
0
0
16
0
0
% Q
% Arg:
0
0
0
0
0
8
0
0
8
0
0
0
0
0
0
% R
% Ser:
16
8
16
54
8
0
8
47
16
8
24
47
24
54
16
% S
% Thr:
0
0
0
0
16
16
16
8
8
8
0
16
31
8
8
% T
% Val:
0
0
0
0
0
16
8
16
47
8
8
8
8
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% W
% Tyr:
8
0
8
0
8
39
8
0
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _