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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: UBE2O All Species: 22.12
Human Site: S475 Identified Species: 40.56
UniProt: Q9C0C9 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9C0C9 NP_071349.3 1292 141293 S475 G R D D R L H S A E Q D A D D
Chimpanzee Pan troglodytes XP_001139963 1392 151306 V473 L Y D V C P H V S D S G L F F
Rhesus Macaque Macaca mulatta XP_001099166 1374 150150 S556 G R D D R L H S A E Q D A D D
Dog Lupus familis XP_540449 1328 145864 S510 G G D D R L H S A E Q D A D D
Cat Felis silvestris
Mouse Mus musculus Q6ZPJ3 1288 140799 S470 G G D D G L H S A E Q D A D D
Rat Rattus norvegicus XP_221132 1291 140971 S473 G G D E G L H S A E Q D A D D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507962 1095 118343 V351 E G S V A K K V K R L L K K Q
Chicken Gallus gallus XP_415619 1288 141077 S476 S A D Y R L Q S M E Q D A D D
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_692656 586 64314
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_651170 1398 156627 T476 Q P L D Q S M T A E K E V E V
Honey Bee Apis mellifera XP_001120701 1287 145895 E503 F V V D Q K E E S R M Y G V V
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002313703 1079 118536 L335 Q V G D W C L L P S S V A Q S
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9ZVX1 1102 122164 K357 P L H K H V S K L R L Y D S Q
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 82.4 93.3 90.9 N.A. 94.1 94.2 N.A. 69.1 77.6 N.A. 28 N.A. 21.8 20.7 N.A. N.A.
Protein Similarity: 100 82.9 93.6 92.9 N.A. 96.1 96 N.A. 74.3 83.9 N.A. 35.2 N.A. 39.9 35.6 N.A. N.A.
P-Site Identity: 100 13.3 100 93.3 N.A. 86.6 80 N.A. 0 66.6 N.A. 0 N.A. 20 6.6 N.A. N.A.
P-Site Similarity: 100 26.6 100 93.3 N.A. 86.6 86.6 N.A. 0 66.6 N.A. 0 N.A. 53.3 20 N.A. N.A.
Percent
Protein Identity: 25.7 N.A. N.A. 23.3 N.A. N.A.
Protein Similarity: 41.8 N.A. N.A. 39.9 N.A. N.A.
P-Site Identity: 13.3 N.A. N.A. 0 N.A. N.A.
P-Site Similarity: 13.3 N.A. N.A. 6.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 0 8 0 0 0 47 0 0 0 54 0 0 % A
% Cys: 0 0 0 0 8 8 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 54 54 0 0 0 0 0 8 0 47 8 47 47 % D
% Glu: 8 0 0 8 0 0 8 8 0 54 0 8 0 8 0 % E
% Phe: 8 0 0 0 0 0 0 0 0 0 0 0 0 8 8 % F
% Gly: 39 31 8 0 16 0 0 0 0 0 0 8 8 0 0 % G
% His: 0 0 8 0 8 0 47 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 8 0 16 8 8 8 0 8 0 8 8 0 % K
% Leu: 8 8 8 0 0 47 8 8 8 0 16 8 8 0 0 % L
% Met: 0 0 0 0 0 0 8 0 8 0 8 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 8 8 0 0 0 8 0 0 8 0 0 0 0 0 0 % P
% Gln: 16 0 0 0 16 0 8 0 0 0 47 0 0 8 16 % Q
% Arg: 0 16 0 0 31 0 0 0 0 24 0 0 0 0 0 % R
% Ser: 8 0 8 0 0 8 8 47 16 8 16 0 0 8 8 % S
% Thr: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % T
% Val: 0 16 8 16 0 8 0 16 0 0 0 8 8 8 16 % V
% Trp: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 0 8 0 0 0 0 0 0 0 16 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _