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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
UBE2O
All Species:
27.27
Human Site:
S399
Identified Species:
50
UniProt:
Q9C0C9
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9C0C9
NP_071349.3
1292
141293
S399
K
Q
V
V
R
I
M
S
C
S
P
D
T
Q
C
Chimpanzee
Pan troglodytes
XP_001139963
1392
151306
N414
N
C
I
I
Y
P
V
N
S
K
D
L
Q
H
I
Rhesus Macaque
Macaca mulatta
XP_001099166
1374
150150
S480
K
Q
V
V
R
I
M
S
C
S
P
D
T
Q
C
Dog
Lupus familis
XP_540449
1328
145864
S434
K
Q
V
V
R
I
M
S
C
S
P
D
T
Q
C
Cat
Felis silvestris
Mouse
Mus musculus
Q6ZPJ3
1288
140799
S394
K
Q
V
V
R
I
M
S
C
T
P
D
T
Q
C
Rat
Rattus norvegicus
XP_221132
1291
140971
S397
K
Q
V
V
R
I
M
S
C
T
P
D
A
Q
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507962
1095
118343
T294
S
P
P
P
S
I
I
T
Q
E
N
L
S
R
V
Chicken
Gallus gallus
XP_415619
1288
141077
S390
K
Q
I
V
K
I
M
S
C
S
P
E
S
Q
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_692656
586
64314
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651170
1398
156627
S403
K
K
M
Q
R
K
A
S
K
L
N
A
S
A
S
Honey Bee
Apis mellifera
XP_001120701
1287
145895
T425
K
K
G
P
A
L
M
T
K
V
L
K
K
K
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002313703
1079
118536
E278
L
W
K
A
N
R
L
E
G
T
V
T
K
V
T
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9ZVX1
1102
122164
A300
S
I
F
V
Y
W
I
A
S
A
G
F
G
P
D
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
82.4
93.3
90.9
N.A.
94.1
94.2
N.A.
69.1
77.6
N.A.
28
N.A.
21.8
20.7
N.A.
N.A.
Protein Similarity:
100
82.9
93.6
92.9
N.A.
96.1
96
N.A.
74.3
83.9
N.A.
35.2
N.A.
39.9
35.6
N.A.
N.A.
P-Site Identity:
100
0
100
100
N.A.
93.3
86.6
N.A.
6.6
66.6
N.A.
0
N.A.
20
13.3
N.A.
N.A.
P-Site Similarity:
100
26.6
100
100
N.A.
100
93.3
N.A.
33.3
93.3
N.A.
0
N.A.
40
40
N.A.
N.A.
Percent
Protein Identity:
25.7
N.A.
N.A.
23.3
N.A.
N.A.
Protein Similarity:
41.8
N.A.
N.A.
39.9
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
8
0
8
8
0
8
0
8
8
8
0
% A
% Cys:
0
8
0
0
0
0
0
0
47
0
0
0
0
0
39
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
8
39
0
0
8
% D
% Glu:
0
0
0
0
0
0
0
8
0
8
0
8
0
0
0
% E
% Phe:
0
0
8
0
0
0
0
0
0
0
0
8
0
0
0
% F
% Gly:
0
0
8
0
0
0
0
0
8
0
8
0
8
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% H
% Ile:
0
8
16
8
0
54
16
0
0
0
0
0
0
0
8
% I
% Lys:
62
16
8
0
8
8
0
0
16
8
0
8
16
8
8
% K
% Leu:
8
0
0
0
0
8
8
0
0
8
8
16
0
0
0
% L
% Met:
0
0
8
0
0
0
54
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
8
0
0
8
0
0
16
0
0
0
0
% N
% Pro:
0
8
8
16
0
8
0
0
0
0
47
0
0
8
0
% P
% Gln:
0
47
0
8
0
0
0
0
8
0
0
0
8
47
0
% Q
% Arg:
0
0
0
0
47
8
0
0
0
0
0
0
0
8
0
% R
% Ser:
16
0
0
0
8
0
0
54
16
31
0
0
24
0
8
% S
% Thr:
0
0
0
0
0
0
0
16
0
24
0
8
31
0
8
% T
% Val:
0
0
39
54
0
0
8
0
0
8
8
0
0
8
8
% V
% Trp:
0
8
0
0
0
8
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
16
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _