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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: UBE2O All Species: 9.7
Human Site: S1210 Identified Species: 17.78
UniProt: Q9C0C9 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9C0C9 NP_071349.3 1292 141293 S1210 G G A Q G L A S A S R D H T D
Chimpanzee Pan troglodytes XP_001139963 1392 151306 I1296 L L Q V L I S I Q G L I L V N
Rhesus Macaque Macaca mulatta XP_001099166 1374 150150 S1292 G G A Q G L A S A S R D H T D
Dog Lupus familis XP_540449 1328 145864 S1246 G G A Q G P A S A S R D R T D
Cat Felis silvestris
Mouse Mus musculus Q6ZPJ3 1288 140799 A1206 E G G A Q G P A S A S R D H T
Rat Rattus norvegicus XP_221132 1291 140971 A1209 E G G A Q G P A S A S R E H P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507962 1095 118343 V1014 L G T W I G K V S E E G L P P
Chicken Gallus gallus XP_415619 1288 141077 V1206 G A G Q G R G V G L A R D R T
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_692656 586 64314 S505 P S V L Y H C S S S K Q D I Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_651170 1398 156627 H1298 F R N E L I E H F K E F G T E
Honey Bee Apis mellifera XP_001120701 1287 145895 E1202 F K E V L I N E N I I E R N S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002313703 1079 118536 F998 M R K P P K D F E D L V K E H
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9ZVX1 1102 122164 E1021 R K P P K D F E E L I K D H F
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 82.4 93.3 90.9 N.A. 94.1 94.2 N.A. 69.1 77.6 N.A. 28 N.A. 21.8 20.7 N.A. N.A.
Protein Similarity: 100 82.9 93.6 92.9 N.A. 96.1 96 N.A. 74.3 83.9 N.A. 35.2 N.A. 39.9 35.6 N.A. N.A.
P-Site Identity: 100 0 100 86.6 N.A. 6.6 6.6 N.A. 6.6 20 N.A. 13.3 N.A. 6.6 0 N.A. N.A.
P-Site Similarity: 100 20 100 86.6 N.A. 26.6 26.6 N.A. 13.3 20 N.A. 26.6 N.A. 26.6 13.3 N.A. N.A.
Percent
Protein Identity: 25.7 N.A. N.A. 23.3 N.A. N.A.
Protein Similarity: 41.8 N.A. N.A. 39.9 N.A. N.A.
P-Site Identity: 0 N.A. N.A. 0 N.A. N.A.
P-Site Similarity: 0 N.A. N.A. 0 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 24 16 0 0 24 16 24 16 8 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 8 8 0 0 8 0 24 31 0 24 % D
% Glu: 16 0 8 8 0 0 8 16 16 8 16 8 8 8 8 % E
% Phe: 16 0 0 0 0 0 8 8 8 0 0 8 0 0 8 % F
% Gly: 31 47 24 0 31 24 8 0 8 8 0 8 8 0 0 % G
% His: 0 0 0 0 0 8 0 8 0 0 0 0 16 24 8 % H
% Ile: 0 0 0 0 8 24 0 8 0 8 16 8 0 8 0 % I
% Lys: 0 16 8 0 8 8 8 0 0 8 8 8 8 0 0 % K
% Leu: 16 8 0 8 24 16 0 0 0 16 16 0 16 0 0 % L
% Met: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 8 0 0 0 8 0 8 0 0 0 0 8 8 % N
% Pro: 8 0 8 16 8 8 16 0 0 0 0 0 0 8 16 % P
% Gln: 0 0 8 31 16 0 0 0 8 0 0 8 0 0 8 % Q
% Arg: 8 16 0 0 0 8 0 0 0 0 24 24 16 8 0 % R
% Ser: 0 8 0 0 0 0 8 31 31 31 16 0 0 0 8 % S
% Thr: 0 0 8 0 0 0 0 0 0 0 0 0 0 31 16 % T
% Val: 0 0 8 16 0 0 0 16 0 0 0 8 0 8 0 % V
% Trp: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _