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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMCO7
All Species:
23.33
Human Site:
T631
Identified Species:
64.17
UniProt:
Q9C0B7
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9C0B7
NP_078838.1
1094
120748
T631
L
E
L
E
Q
H
Q
T
L
L
V
E
G
Q
E
Chimpanzee
Pan troglodytes
XP_511059
1095
120615
T632
L
E
L
E
Q
H
Q
T
L
L
V
E
G
Q
E
Rhesus Macaque
Macaca mulatta
XP_001092854
1140
125131
T677
L
E
L
E
Q
Y
Q
T
L
L
V
E
G
Q
E
Dog
Lupus familis
XP_546861
1144
127481
T685
L
E
L
E
Q
H
Q
T
L
V
E
G
Q
E
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8C3S2
1079
118714
T635
L
E
L
E
H
H
Q
T
L
L
I
E
D
Q
E
Rat
Rattus norvegicus
XP_002725457
1039
115179
T633
L
E
L
E
Q
H
Q
T
L
L
I
E
D
Q
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510457
1107
121829
T633
L
Y
L
E
Q
R
N
T
S
R
I
A
R
Q
E
Chicken
Gallus gallus
XP_414221
849
91597
D468
A
V
Q
L
K
S
S
D
F
A
V
L
K
R
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_683380
1065
116598
L604
L
E
L
E
Q
H
L
L
G
R
V
S
G
H
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
89.5
79.6
N.A.
81.9
78.7
N.A.
68.3
49.5
N.A.
47.9
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.4
92.3
85.8
N.A.
88.6
85.4
N.A.
81.3
59.5
N.A.
63.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
60
N.A.
80
86.6
N.A.
46.6
6.6
N.A.
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
80
N.A.
86.6
93.3
N.A.
53.3
20
N.A.
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
0
0
0
0
0
0
0
12
0
12
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
12
0
0
0
0
23
0
0
% D
% Glu:
0
78
0
89
0
0
0
0
0
0
12
56
0
12
67
% E
% Phe:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
12
0
0
12
45
0
12
% G
% His:
0
0
0
0
12
67
0
0
0
0
0
0
0
12
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
34
0
0
0
0
% I
% Lys:
0
0
0
0
12
0
0
0
0
0
0
0
12
0
0
% K
% Leu:
89
0
89
12
0
0
12
12
67
56
0
12
0
0
12
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
12
0
78
0
67
0
0
0
0
0
12
67
12
% Q
% Arg:
0
0
0
0
0
12
0
0
0
23
0
0
12
12
0
% R
% Ser:
0
0
0
0
0
12
12
0
12
0
0
12
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
78
0
0
0
0
0
0
0
% T
% Val:
0
12
0
0
0
0
0
0
0
12
56
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
12
0
0
0
12
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _