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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZDHHC5
All Species:
16.67
Human Site:
S499
Identified Species:
52.38
UniProt:
Q9C0B5
Number Species:
7
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9C0B5
NP_056272.2
715
77545
S499
D
P
P
L
G
Y
T
S
P
F
L
S
A
R
L
Chimpanzee
Pan troglodytes
Q2THX1
715
77568
S499
D
P
P
L
G
Y
T
S
P
F
L
S
A
R
L
Rhesus Macaque
Macaca mulatta
XP_001106616
759
80860
V499
A
C
P
A
H
P
A
V
G
V
A
G
Y
H
S
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q8VDZ4
715
77482
S499
D
P
P
L
G
Y
T
S
P
F
L
S
A
R
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001034689
740
79705
S516
D
P
P
V
G
Y
T
S
P
F
L
S
A
R
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_840089
751
82866
S499
V
P
S
M
G
F
H
S
P
Y
L
P
T
K
M
Tiger Blowfish
Takifugu rubipres
NP_001072064
797
88276
H514
L
S
Y
D
S
L
L
H
P
S
I
S
S
A
T
Fruit Fly
Dros. melanogaster
NP_727339
934
99698
R494
A
T
P
T
M
Q
Q
R
I
K
P
L
G
V
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
46.6
N.A.
N.A.
97.9
N.A.
N.A.
N.A.
81.8
N.A.
49.2
47
28.2
N.A.
N.A.
N.A.
Protein Similarity:
100
99.8
58.6
N.A.
N.A.
98.5
N.A.
N.A.
N.A.
86.7
N.A.
62.8
58.5
42.4
N.A.
N.A.
N.A.
P-Site Identity:
100
100
6.6
N.A.
N.A.
100
N.A.
N.A.
N.A.
86.6
N.A.
33.3
13.3
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
6.6
N.A.
N.A.
100
N.A.
N.A.
N.A.
100
N.A.
66.6
26.6
6.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
25
0
0
13
0
0
13
0
0
0
13
0
50
13
13
% A
% Cys:
0
13
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
50
0
0
13
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
13
0
0
0
50
0
0
0
0
0
% F
% Gly:
0
0
0
0
63
0
0
0
13
0
0
13
13
0
0
% G
% His:
0
0
0
0
13
0
13
13
0
0
0
0
0
13
0
% H
% Ile:
0
0
0
0
0
0
0
0
13
0
13
0
0
0
13
% I
% Lys:
0
0
0
0
0
0
0
0
0
13
0
0
0
13
0
% K
% Leu:
13
0
0
38
0
13
13
0
0
0
63
13
0
0
38
% L
% Met:
0
0
0
13
13
0
0
0
0
0
0
0
0
0
13
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
63
75
0
0
13
0
0
75
0
13
13
0
0
0
% P
% Gln:
0
0
0
0
0
13
13
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
13
0
0
0
0
0
50
0
% R
% Ser:
0
13
13
0
13
0
0
63
0
13
0
63
13
0
13
% S
% Thr:
0
13
0
13
0
0
50
0
0
0
0
0
13
0
13
% T
% Val:
13
0
0
13
0
0
0
13
0
13
0
0
0
13
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
13
0
0
50
0
0
0
13
0
0
13
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _