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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NKX6-2
All Species:
37.88
Human Site:
T166
Identified Species:
75.76
UniProt:
Q9C056
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9C056
NP_796374.1
277
29263
T166
Q
I
F
A
L
E
K
T
F
E
Q
T
K
Y
L
Chimpanzee
Pan troglodytes
XP_521638
440
46674
T166
Q
I
F
A
L
E
K
T
F
E
Q
T
K
Y
L
Rhesus Macaque
Macaca mulatta
XP_001092370
277
29234
T166
Q
I
F
A
L
E
K
T
F
E
Q
T
K
Y
L
Dog
Lupus familis
XP_544960
366
37787
T255
Q
I
F
A
L
E
K
T
F
E
Q
T
K
Y
L
Cat
Felis silvestris
Mouse
Mus musculus
Q99MA9
365
37687
T255
Q
I
F
A
L
E
K
T
F
E
Q
T
K
Y
L
Rat
Rattus norvegicus
O35762
365
37671
T255
Q
I
F
A
L
E
K
T
F
E
Q
T
K
Y
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510049
265
28997
T157
Q
I
F
A
L
E
K
T
F
E
Q
T
K
Y
L
Chicken
Gallus gallus
Q9DE09
333
34878
T219
Q
V
F
Q
L
E
S
T
F
D
V
K
R
Y
L
Frog
Xenopus laevis
A5YC49
254
27880
H135
E
G
S
S
R
K
K
H
T
R
P
T
F
T
G
Zebra Danio
Brachydanio rerio
Q504H8
297
33069
T188
Q
V
F
Q
L
E
S
T
F
D
M
K
R
Y
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P56407
147
17231
T39
K
D
I
L
D
L
P
T
V
N
G
E
I
D
E
Sea Urchin
Strong. purpuratus
Q26656
405
44721
T271
Q
V
F
Q
L
E
S
T
F
E
V
K
R
Y
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
61.3
98.5
53.5
N.A.
54.2
54.5
N.A.
49.4
25.8
44.4
22.2
N.A.
N.A.
N.A.
26.7
23.7
Protein Similarity:
100
61.8
99.2
59.5
N.A.
60.8
60.2
N.A.
61.7
38.4
55.9
37.3
N.A.
N.A.
N.A.
38.2
35
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
100
53.3
13.3
53.3
N.A.
N.A.
N.A.
6.6
60
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
73.3
33.3
73.3
N.A.
N.A.
N.A.
13.3
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
59
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
0
0
9
0
0
0
0
17
0
0
0
9
0
% D
% Glu:
9
0
0
0
0
84
0
0
0
67
0
9
0
0
9
% E
% Phe:
0
0
84
0
0
0
0
0
84
0
0
0
9
0
0
% F
% Gly:
0
9
0
0
0
0
0
0
0
0
9
0
0
0
9
% G
% His:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% H
% Ile:
0
59
9
0
0
0
0
0
0
0
0
0
9
0
0
% I
% Lys:
9
0
0
0
0
9
67
0
0
0
0
25
59
0
0
% K
% Leu:
0
0
0
9
84
9
0
0
0
0
0
0
0
0
84
% L
% Met:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
9
0
0
0
9
0
0
0
0
% P
% Gln:
84
0
0
25
0
0
0
0
0
0
59
0
0
0
0
% Q
% Arg:
0
0
0
0
9
0
0
0
0
9
0
0
25
0
0
% R
% Ser:
0
0
9
9
0
0
25
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
92
9
0
0
67
0
9
0
% T
% Val:
0
25
0
0
0
0
0
0
9
0
17
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
84
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _