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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NKX6-2
All Species:
12.73
Human Site:
S28
Identified Species:
25.45
UniProt:
Q9C056
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9C056
NP_796374.1
277
29263
S28
N
M
A
E
M
K
T
S
L
F
P
Y
A
L
Q
Chimpanzee
Pan troglodytes
XP_521638
440
46674
S28
N
M
A
E
M
K
T
S
L
F
P
Y
A
L
Q
Rhesus Macaque
Macaca mulatta
XP_001092370
277
29234
S28
N
M
A
E
M
K
T
S
L
F
P
Y
A
L
Q
Dog
Lupus familis
XP_544960
366
37787
P34
S
M
A
E
M
K
T
P
L
Y
P
A
A
Y
P
Cat
Felis silvestris
Mouse
Mus musculus
Q99MA9
365
37687
P34
S
M
A
E
M
K
T
P
L
Y
P
A
A
Y
P
Rat
Rattus norvegicus
O35762
365
37671
P34
S
M
A
E
M
K
T
P
L
Y
P
A
A
Y
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510049
265
28997
Q28
E
M
K
A
P
M
C
Q
Y
A
M
Q
N
S
F
Chicken
Gallus gallus
Q9DE09
333
34878
S46
R
G
A
E
E
P
S
S
G
G
A
G
T
P
P
Frog
Xenopus laevis
A5YC49
254
27880
T28
G
C
Q
F
P
T
H
T
P
F
H
K
L
N
P
Zebra Danio
Brachydanio rerio
Q504H8
297
33069
P29
L
L
N
S
D
S
K
P
S
K
P
K
P
I
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P56407
147
17231
Sea Urchin
Strong. purpuratus
Q26656
405
44721
S41
H
P
A
R
P
P
A
S
L
A
S
Q
P
L
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
61.3
98.5
53.5
N.A.
54.2
54.5
N.A.
49.4
25.8
44.4
22.2
N.A.
N.A.
N.A.
26.7
23.7
Protein Similarity:
100
61.8
99.2
59.5
N.A.
60.8
60.2
N.A.
61.7
38.4
55.9
37.3
N.A.
N.A.
N.A.
38.2
35
P-Site Identity:
100
100
100
60
N.A.
60
60
N.A.
6.6
20
6.6
6.6
N.A.
N.A.
N.A.
0
26.6
P-Site Similarity:
100
100
100
73.3
N.A.
73.3
73.3
N.A.
6.6
26.6
13.3
20
N.A.
N.A.
N.A.
0
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
67
9
0
0
9
0
0
17
9
25
50
0
0
% A
% Cys:
0
9
0
0
0
0
9
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
9
0
0
59
9
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
9
0
0
0
0
0
34
0
0
0
0
9
% F
% Gly:
9
9
0
0
0
0
0
0
9
9
0
9
0
0
0
% G
% His:
9
0
0
0
0
0
9
0
0
0
9
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% I
% Lys:
0
0
9
0
0
50
9
0
0
9
0
17
0
0
0
% K
% Leu:
9
9
0
0
0
0
0
0
59
0
0
0
9
34
9
% L
% Met:
0
59
0
0
50
9
0
0
0
0
9
0
0
0
0
% M
% Asn:
25
0
9
0
0
0
0
0
0
0
0
0
9
9
0
% N
% Pro:
0
9
0
0
25
17
0
34
9
0
59
0
17
9
42
% P
% Gln:
0
0
9
0
0
0
0
9
0
0
0
17
0
0
25
% Q
% Arg:
9
0
0
9
0
0
0
0
0
0
0
0
0
0
9
% R
% Ser:
25
0
0
9
0
9
9
42
9
0
9
0
0
9
0
% S
% Thr:
0
0
0
0
0
9
50
9
0
0
0
0
9
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
9
25
0
25
0
25
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _