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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NKX6-2
All Species:
18.18
Human Site:
S246
Identified Species:
36.36
UniProt:
Q9C056
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9C056
NP_796374.1
277
29263
S246
N
R
P
L
D
P
N
S
D
D
E
K
I
T
R
Chimpanzee
Pan troglodytes
XP_521638
440
46674
D246
R
P
L
D
P
N
S
D
D
E
K
I
T
R
L
Rhesus Macaque
Macaca mulatta
XP_001092370
277
29234
S246
N
R
P
L
D
P
N
S
D
D
E
K
I
T
R
Dog
Lupus familis
XP_544960
366
37787
S335
N
K
P
L
D
P
N
S
D
D
E
K
I
T
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q99MA9
365
37687
S335
N
K
P
L
D
P
N
S
D
D
E
K
I
T
Q
Rat
Rattus norvegicus
O35762
365
37671
S335
N
K
P
L
D
P
N
S
D
D
E
K
I
T
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510049
265
28997
P237
E
Y
N
K
P
L
D
P
D
S
D
D
E
K
I
Chicken
Gallus gallus
Q9DE09
333
34878
M299
L
G
F
G
L
P
H
M
S
P
P
L
V
G
F
Frog
Xenopus laevis
A5YC49
254
27880
N215
G
D
L
I
P
S
D
N
E
D
D
E
Y
S
K
Zebra Danio
Brachydanio rerio
Q504H8
297
33069
V268
S
T
N
T
A
G
N
V
P
V
S
Q
P
L
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P56407
147
17231
Q119
T
Q
V
K
I
W
F
Q
N
R
R
T
K
W
K
Sea Urchin
Strong. purpuratus
Q26656
405
44721
V351
Y
A
Q
R
M
V
R
V
P
I
L
Y
H
E
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
61.3
98.5
53.5
N.A.
54.2
54.5
N.A.
49.4
25.8
44.4
22.2
N.A.
N.A.
N.A.
26.7
23.7
Protein Similarity:
100
61.8
99.2
59.5
N.A.
60.8
60.2
N.A.
61.7
38.4
55.9
37.3
N.A.
N.A.
N.A.
38.2
35
P-Site Identity:
100
6.6
100
86.6
N.A.
86.6
86.6
N.A.
6.6
6.6
6.6
6.6
N.A.
N.A.
N.A.
0
0
P-Site Similarity:
100
26.6
100
100
N.A.
100
100
N.A.
20
20
60
20
N.A.
N.A.
N.A.
20
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
9
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
0
9
42
0
17
9
59
50
17
9
0
0
0
% D
% Glu:
9
0
0
0
0
0
0
0
9
9
42
9
9
9
0
% E
% Phe:
0
0
9
0
0
0
9
0
0
0
0
0
0
0
9
% F
% Gly:
9
9
0
9
0
9
0
0
0
0
0
0
0
9
0
% G
% His:
0
0
0
0
0
0
9
0
0
0
0
0
9
0
0
% H
% Ile:
0
0
0
9
9
0
0
0
0
9
0
9
42
0
9
% I
% Lys:
0
25
0
17
0
0
0
0
0
0
9
42
9
9
17
% K
% Leu:
9
0
17
42
9
9
0
0
0
0
9
9
0
9
17
% L
% Met:
0
0
0
0
9
0
0
9
0
0
0
0
0
0
0
% M
% Asn:
42
0
17
0
0
9
50
9
9
0
0
0
0
0
9
% N
% Pro:
0
9
42
0
25
50
0
9
17
9
9
0
9
0
0
% P
% Gln:
0
9
9
0
0
0
0
9
0
0
0
9
0
0
25
% Q
% Arg:
9
17
0
9
0
0
9
0
0
9
9
0
0
9
17
% R
% Ser:
9
0
0
0
0
9
9
42
9
9
9
0
0
9
0
% S
% Thr:
9
9
0
9
0
0
0
0
0
0
0
9
9
42
0
% T
% Val:
0
0
9
0
0
9
0
17
0
9
0
0
9
0
0
% V
% Trp:
0
0
0
0
0
9
0
0
0
0
0
0
0
9
0
% W
% Tyr:
9
9
0
0
0
0
0
0
0
0
0
9
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _