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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TM6SF1
All Species:
34.24
Human Site:
Y136
Identified Species:
75.33
UniProt:
Q9BZW5
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BZW5
NP_001138375.1
370
41636
Y136
A
I
A
W
E
E
T
Y
R
T
I
G
L
Y
W
Chimpanzee
Pan troglodytes
XP_510557
371
41677
Y137
A
I
A
W
E
E
T
Y
R
T
I
G
L
Y
W
Rhesus Macaque
Macaca mulatta
XP_001088546
374
42104
Y140
A
I
A
W
E
E
T
Y
R
T
I
G
L
Y
W
Dog
Lupus familis
XP_536207
385
43331
Y151
A
I
A
W
E
E
S
Y
R
T
I
G
L
Y
W
Cat
Felis silvestris
Mouse
Mus musculus
P58749
370
41630
Y136
A
I
A
W
E
E
S
Y
R
T
I
G
L
Y
W
Rat
Rattus norvegicus
NP_001101960
345
39152
I123
L
Y
W
V
G
S
I
I
M
S
I
V
V
F
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513106
345
39369
A117
L
Y
W
L
G
S
L
A
M
S
I
L
V
F
L
Chicken
Gallus gallus
XP_413840
370
41520
Y136
A
I
A
W
E
Q
S
Y
R
T
I
G
L
Y
W
Frog
Xenopus laevis
Q6DCP8
370
41347
Y136
A
I
A
W
D
Q
T
Y
R
T
I
G
L
Y
W
Zebra Danio
Brachydanio rerio
NP_001074130
374
42382
Y134
R
M
S
S
R
Q
Q
Y
R
T
L
G
L
F
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793469
381
42849
Y138
A
I
V
W
G
Q
S
Y
R
E
V
G
L
Y
W
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
90.9
86.7
N.A.
94.5
87
N.A.
49.1
80.5
68.1
43.8
N.A.
N.A.
N.A.
N.A.
47.7
Protein Similarity:
100
99.4
92.2
90.1
N.A.
97.8
90.8
N.A.
67.8
89.7
81
63.3
N.A.
N.A.
N.A.
N.A.
64.3
P-Site Identity:
100
100
100
93.3
N.A.
93.3
6.6
N.A.
6.6
86.6
86.6
40
N.A.
N.A.
N.A.
N.A.
60
P-Site Similarity:
100
100
100
100
N.A.
100
26.6
N.A.
26.6
100
100
73.3
N.A.
N.A.
N.A.
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
73
0
64
0
0
0
0
10
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
55
46
0
0
0
10
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
28
0
% F
% Gly:
0
0
0
0
28
0
0
0
0
0
0
82
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
73
0
0
0
0
10
10
0
0
82
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
19
0
0
10
0
0
10
0
0
0
10
10
82
0
10
% L
% Met:
0
10
0
0
0
0
0
0
19
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
37
10
0
0
0
0
0
0
0
0
% Q
% Arg:
10
0
0
0
10
0
0
0
82
0
0
0
0
0
0
% R
% Ser:
0
0
10
10
0
19
37
0
0
19
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
37
0
0
73
0
0
0
0
0
% T
% Val:
0
0
10
10
0
0
0
0
0
0
10
10
19
0
10
% V
% Trp:
0
0
19
73
0
0
0
0
0
0
0
0
0
0
82
% W
% Tyr:
0
19
0
0
0
0
0
82
0
0
0
0
0
73
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _