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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC19A3
All Species:
4.85
Human Site:
T461
Identified Species:
10.67
UniProt:
Q9BZV2
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BZV2
NP_079519.1
496
55665
T461
L
M
R
S
M
Y
I
T
Y
S
T
K
S
Q
K
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001111429
496
55875
I461
L
M
R
S
M
Y
I
I
Y
S
T
K
S
Q
K
Dog
Lupus familis
XP_543277
608
66821
I573
L
T
R
S
M
Y
I
I
Y
S
T
R
C
Q
K
Cat
Felis silvestris
Mouse
Mus musculus
Q99PL8
488
55054
I454
F
L
M
R
S
I
Y
I
L
C
S
A
K
C
R
Rat
Rattus norvegicus
Q62866
512
58076
Q478
S
V
Q
A
I
S
L
Q
D
G
D
L
R
R
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506095
278
31139
Y244
W
A
A
A
T
A
G
Y
N
Q
V
V
N
Y
V
Chicken
Gallus gallus
XP_422610
474
52428
S440
T
Q
F
L
V
Y
S
S
Y
F
T
F
I
A
G
Frog
Xenopus laevis
NP_001084859
491
55284
Y457
Q
F
K
I
Y
A
G
Y
F
T
A
I
S
L
I
Zebra Danio
Brachydanio rerio
XP_002662367
478
53350
S444
I
Q
F
L
I
Y
A
S
Y
F
A
A
V
A
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q17766
410
46514
F376
A
S
I
F
A
F
F
F
M
I
S
L
F
S
K
Sea Urchin
Strong. purpuratus
XP_791719
533
60255
A462
C
I
K
A
V
Y
Q
A
G
Q
R
G
C
R
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
94.7
67.5
N.A.
68.3
37.1
N.A.
36.9
59.4
48.9
51.4
N.A.
N.A.
N.A.
32.2
42.7
Protein Similarity:
100
N.A.
97.3
72.8
N.A.
80
57.8
N.A.
44.9
75.4
65.1
67.9
N.A.
N.A.
N.A.
53.4
61.3
P-Site Identity:
100
N.A.
93.3
73.3
N.A.
0
0
N.A.
0
20
6.6
13.3
N.A.
N.A.
N.A.
6.6
6.6
P-Site Similarity:
100
N.A.
93.3
80
N.A.
20
40
N.A.
13.3
33.3
26.6
33.3
N.A.
N.A.
N.A.
20
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
10
28
10
19
10
10
0
0
19
19
0
19
0
% A
% Cys:
10
0
0
0
0
0
0
0
0
10
0
0
19
10
0
% C
% Asp:
0
0
0
0
0
0
0
0
10
0
10
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
10
10
19
10
0
10
10
10
10
19
0
10
10
0
0
% F
% Gly:
0
0
0
0
0
0
19
0
10
10
0
10
0
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
10
10
10
19
10
28
28
0
10
0
10
10
0
10
% I
% Lys:
0
0
19
0
0
0
0
0
0
0
0
19
10
0
37
% K
% Leu:
28
10
0
19
0
0
10
0
10
0
0
19
0
10
0
% L
% Met:
0
19
10
0
28
0
0
0
10
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
10
0
0
0
10
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% P
% Gln:
10
19
10
0
0
0
10
10
0
19
0
0
0
28
10
% Q
% Arg:
0
0
28
10
0
0
0
0
0
0
10
10
10
19
10
% R
% Ser:
10
10
0
28
10
10
10
19
0
28
19
0
28
10
0
% S
% Thr:
10
10
0
0
10
0
0
10
0
10
37
0
0
0
0
% T
% Val:
0
10
0
0
19
0
0
0
0
0
10
10
10
0
19
% V
% Trp:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
10
55
10
19
46
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _