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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC19A3
All Species:
4.55
Human Site:
S251
Identified Species:
10
UniProt:
Q9BZV2
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BZV2
NP_079519.1
496
55665
S251
L
N
K
G
Q
L
N
S
L
K
P
S
N
V
T
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001111429
496
55875
S251
L
H
K
G
Q
L
N
S
L
K
P
R
N
V
T
Dog
Lupus familis
XP_543277
608
66821
P364
D
G
A
P
V
N
S
P
M
P
K
N
L
V
L
Cat
Felis silvestris
Mouse
Mus musculus
Q99PL8
488
55054
P246
E
D
R
E
M
S
N
P
D
P
E
N
S
A
L
Rat
Rattus norvegicus
Q62866
512
58076
V262
L
S
E
L
V
K
N
V
R
Q
P
Q
L
R
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506095
278
31139
Q36
Y
K
P
I
I
V
L
Q
G
I
S
F
L
I
T
Chicken
Gallus gallus
XP_422610
474
52428
C232
S
C
Q
Q
D
K
G
C
A
P
A
D
T
G
P
Frog
Xenopus laevis
NP_001084859
491
55284
L249
E
I
E
S
R
I
A
L
N
S
E
I
R
S
E
Zebra Danio
Brachydanio rerio
XP_002662367
478
53350
K236
N
T
S
P
L
I
E
K
P
E
D
P
E
S
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q17766
410
46514
L168
L
V
L
N
Q
I
S
L
G
A
V
C
L
V
T
Sea Urchin
Strong. purpuratus
XP_791719
533
60255
S252
E
R
T
L
S
C
F
S
S
T
K
R
F
S
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
94.7
67.5
N.A.
68.3
37.1
N.A.
36.9
59.4
48.9
51.4
N.A.
N.A.
N.A.
32.2
42.7
Protein Similarity:
100
N.A.
97.3
72.8
N.A.
80
57.8
N.A.
44.9
75.4
65.1
67.9
N.A.
N.A.
N.A.
53.4
61.3
P-Site Identity:
100
N.A.
86.6
6.6
N.A.
6.6
20
N.A.
6.6
0
0
0
N.A.
N.A.
N.A.
26.6
6.6
P-Site Similarity:
100
N.A.
93.3
26.6
N.A.
33.3
40
N.A.
20
6.6
20
13.3
N.A.
N.A.
N.A.
40
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
0
10
0
10
10
10
0
0
10
0
% A
% Cys:
0
10
0
0
0
10
0
10
0
0
0
10
0
0
0
% C
% Asp:
10
10
0
0
10
0
0
0
10
0
10
10
0
0
0
% D
% Glu:
28
0
19
10
0
0
10
0
0
10
19
0
10
0
10
% E
% Phe:
0
0
0
0
0
0
10
0
0
0
0
10
10
0
0
% F
% Gly:
0
10
0
19
0
0
10
0
19
0
0
0
0
10
0
% G
% His:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
10
% H
% Ile:
0
10
0
10
10
28
0
0
0
10
0
10
0
10
0
% I
% Lys:
0
10
19
0
0
19
0
10
0
19
19
0
0
0
0
% K
% Leu:
37
0
10
19
10
19
10
19
19
0
0
0
37
0
28
% L
% Met:
0
0
0
0
10
0
0
0
10
0
0
0
0
0
0
% M
% Asn:
10
10
0
10
0
10
37
0
10
0
0
19
19
0
10
% N
% Pro:
0
0
10
19
0
0
0
19
10
28
28
10
0
0
10
% P
% Gln:
0
0
10
10
28
0
0
10
0
10
0
10
0
0
0
% Q
% Arg:
0
10
10
0
10
0
0
0
10
0
0
19
10
10
0
% R
% Ser:
10
10
10
10
10
10
19
28
10
10
10
10
10
28
0
% S
% Thr:
0
10
10
0
0
0
0
0
0
10
0
0
10
0
37
% T
% Val:
0
10
0
0
19
10
0
10
0
0
10
0
0
37
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _