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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PUS3 All Species: 21.21
Human Site: S39 Identified Species: 33.33
UniProt: Q9BZE2 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.21
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BZE2 NP_112597.3 481 55647 S39 Q A K N K E D S N I R E N S A
Chimpanzee Pan troglodytes XP_001148378 481 55605 S39 Q A K N K E D S N I R E N S S
Rhesus Macaque Macaca mulatta XP_001111887 480 55510 S38 Q A K N K E D S N I R K N S S
Dog Lupus familis XP_536533 480 55541 S38 E Q A N N K D S N A R E N S L
Cat Felis silvestris
Mouse Mus musculus Q9JI38 481 55528 S40 Q A N N I K D S S I R E N S L
Rat Rattus norvegicus NP_001101604 479 54918 T38 Q A N N I K D T S V R E N S L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519338 695 77635 R37 Q R G R A D G R E D P A A G G
Chicken Gallus gallus XP_417852 390 44604
Frog Xenopus laevis NP_001093370 507 57122 G35 C R G E G D Q G L R H T N P K
Zebra Danio Brachydanio rerio NP_956361 460 52863 T34 E T E E K S Q T S E S G S R Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_611646 499 57673 V75 G N E A E G K V S Q V A K T S
Honey Bee Apis mellifera XP_393954 406 48319 Q14 D K T Q E T L Q K E E L Q L L
Nematode Worm Caenorhab. elegans Q09524 402 46272 A10 S K R V C P D A N N S V K S K
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002302151 465 53086 K69 E M N S G C K K S G R K K A T
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P31115 442 50870 K26 T N A I V S K K D S I Y A N W
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 96.4 88.3 N.A. 85.2 83.5 N.A. 48.2 57.7 52.4 50.5 N.A. 37.2 39 31.3 N.A.
Protein Similarity: 100 99.5 98.3 92.9 N.A. 90.6 88.5 N.A. 57.4 67.7 67.8 65 N.A. 54.7 58.4 49.2 N.A.
P-Site Identity: 100 93.3 86.6 53.3 N.A. 66.6 53.3 N.A. 6.6 0 6.6 6.6 N.A. 0 0 20 N.A.
P-Site Similarity: 100 100 100 66.6 N.A. 80 80 N.A. 13.3 0 13.3 40 N.A. 33.3 6.6 33.3 N.A.
Percent
Protein Identity: 38.2 N.A. N.A. N.A. 37.2 N.A.
Protein Similarity: 56.5 N.A. N.A. N.A. 53 N.A.
P-Site Identity: 6.6 N.A. N.A. N.A. 0 N.A.
P-Site Similarity: 40 N.A. N.A. N.A. 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 34 14 7 7 0 0 7 0 7 0 14 14 7 7 % A
% Cys: 7 0 0 0 7 7 0 0 0 0 0 0 0 0 0 % C
% Asp: 7 0 0 0 0 14 47 0 7 7 0 0 0 0 0 % D
% Glu: 20 0 14 14 14 20 0 0 7 14 7 34 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 7 0 14 0 14 7 7 7 0 7 0 7 0 7 7 % G
% His: 0 0 0 0 0 0 0 0 0 0 7 0 0 0 0 % H
% Ile: 0 0 0 7 14 0 0 0 0 27 7 0 0 0 0 % I
% Lys: 0 14 20 0 27 20 20 14 7 0 0 14 20 0 14 % K
% Leu: 0 0 0 0 0 0 7 0 7 0 0 7 0 7 27 % L
% Met: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 14 20 40 7 0 0 0 34 7 0 0 47 7 0 % N
% Pro: 0 0 0 0 0 7 0 0 0 0 7 0 0 7 0 % P
% Gln: 40 7 0 7 0 0 14 7 0 7 0 0 7 0 7 % Q
% Arg: 0 14 7 7 0 0 0 7 0 7 47 0 0 7 0 % R
% Ser: 7 0 0 7 0 14 0 34 34 7 14 0 7 47 20 % S
% Thr: 7 7 7 0 0 7 0 14 0 0 0 7 0 7 7 % T
% Val: 0 0 0 7 7 0 0 7 0 7 7 7 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _