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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AGXT2 All Species: 23.33
Human Site: S244 Identified Species: 39.49
UniProt: Q9BYV1 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BYV1 NP_114106.1 514 57156 S244 G G S H C R D S P V Q T I R K
Chimpanzee Pan troglodytes XP_526951 513 57215 S243 G G S H C R D S P V Q T I R K
Rhesus Macaque Macaca mulatta XP_001090812 514 57272 S244 G G S H C R D S P V Q T I R K
Dog Lupus familis XP_855415 520 57365 S250 G G S H C R D S P V Q T I R K
Cat Felis silvestris
Mouse Mus musculus Q3UEG6 513 57096 S243 G G I H C R D S P V Q T V R D
Rat Rattus norvegicus Q64565 512 57182 S242 G G S H C R D S P V Q T V R K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509172 497 55013 T229 C R D S P V Q T I R K C S C A
Chicken Gallus gallus XP_429219 467 51928 V230 K D T L N T S V P K T I A G F
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q7SY54 492 54717 Q251 I F I A D E V Q V G F G R V G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VU95 494 54265 Y243 Q I L P P A G Y F Q A V Y D A
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P91408 467 51626 R232 I L N D V E S R Q C G V A A Y
Sea Urchin Strong. purpuratus XP_001186664 454 50395 A226 K K I A G F F A E G I Q G V G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q940M2 476 51934 K237 S D G S L Y A K D V H D H I E
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q9P3I3 461 49389 S236 N D I A A I P S L V T E K T C
Conservation
Percent
Protein Identity: 100 98.8 96.6 81.7 N.A. 84.8 83 N.A. 67.1 64 N.A. 34 N.A. 35.9 N.A. 31.9 54
Protein Similarity: 100 99 98.2 88.6 N.A. 91.6 89.6 N.A. 80.7 76.6 N.A. 51.9 N.A. 53.3 N.A. 50 67.1
P-Site Identity: 100 100 100 100 N.A. 80 93.3 N.A. 0 6.6 N.A. 0 N.A. 0 N.A. 0 0
P-Site Similarity: 100 100 100 100 N.A. 86.6 100 N.A. 13.3 13.3 N.A. 0 N.A. 0 N.A. 6.6 6.6
Percent
Protein Identity: N.A. N.A. N.A. 44.5 N.A. 27.6
Protein Similarity: N.A. N.A. N.A. 60.7 N.A. 45.5
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. 13.3
P-Site Similarity: N.A. N.A. N.A. 13.3 N.A. 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 22 8 8 8 8 0 0 8 0 15 8 15 % A
% Cys: 8 0 0 0 43 0 0 0 0 8 0 8 0 8 8 % C
% Asp: 0 22 8 8 8 0 43 0 8 0 0 8 0 8 8 % D
% Glu: 0 0 0 0 0 15 0 0 8 0 0 8 0 0 8 % E
% Phe: 0 8 0 0 0 8 8 0 8 0 8 0 0 0 8 % F
% Gly: 43 43 8 0 8 0 8 0 0 15 8 8 8 8 15 % G
% His: 0 0 0 43 0 0 0 0 0 0 8 0 8 0 0 % H
% Ile: 15 8 29 0 0 8 0 0 8 0 8 8 29 8 0 % I
% Lys: 15 8 0 0 0 0 0 8 0 8 8 0 8 0 36 % K
% Leu: 0 8 8 8 8 0 0 0 8 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 8 0 8 0 8 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 8 15 0 8 0 50 0 0 0 0 0 0 % P
% Gln: 8 0 0 0 0 0 8 8 8 8 43 8 0 0 0 % Q
% Arg: 0 8 0 0 0 43 0 8 0 8 0 0 8 43 0 % R
% Ser: 8 0 36 15 0 0 15 50 0 0 0 0 8 0 0 % S
% Thr: 0 0 8 0 0 8 0 8 0 0 15 43 0 8 0 % T
% Val: 0 0 0 0 8 8 8 8 8 58 0 15 15 15 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 8 0 8 0 0 0 0 8 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _