KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HES7
All Species:
18.18
Human Site:
Y125
Identified Species:
40
UniProt:
Q9BYE0
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BYE0
NP_115969.2
225
24894
Y125
L
F
S
A
L
H
G
Y
L
R
P
K
P
P
R
Chimpanzee
Pan troglodytes
XP_001167471
225
24844
Y125
L
F
S
A
L
H
G
Y
L
R
P
K
P
P
R
Rhesus Macaque
Macaca mulatta
XP_001118139
272
29941
Y172
L
F
S
A
L
H
G
Y
L
R
P
K
P
P
R
Dog
Lupus familis
XP_850055
65
7913
Cat
Felis silvestris
Mouse
Mus musculus
Q8BKT2
225
24871
Y125
L
F
S
A
L
H
G
Y
R
R
P
K
P
P
R
Rat
Rattus norvegicus
Q03062
166
18434
L103
L
Q
E
A
V
Q
F
L
T
L
H
A
A
S
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509464
376
41515
Y187
L
L
T
T
L
H
G
Y
L
H
P
K
P
Q
R
Chicken
Gallus gallus
O57337
290
31053
H143
V
R
A
R
L
L
G
H
L
S
A
C
L
G
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6QB00
270
30843
K174
I
L
A
F
L
Q
S
K
V
V
T
E
P
V
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q26263
435
46532
N269
I
A
N
P
T
H
L
N
D
Y
T
Q
S
F
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001001768
400
42683
T137
L
I
N
H
L
A
N
T
C
N
P
P
T
P
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
81.2
27.1
N.A.
92
32.4
N.A.
36.4
25.8
N.A.
21.4
N.A.
22.7
N.A.
N.A.
24.7
Protein Similarity:
100
99.1
81.6
27.1
N.A.
94.2
41.3
N.A.
43.3
39.6
N.A.
33.3
N.A.
34
N.A.
N.A.
33.2
P-Site Identity:
100
100
100
0
N.A.
93.3
13.3
N.A.
66.6
20
N.A.
13.3
N.A.
13.3
N.A.
N.A.
26.6
P-Site Similarity:
100
100
100
0
N.A.
93.3
20
N.A.
73.3
46.6
N.A.
40
N.A.
33.3
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
19
46
0
10
0
0
0
0
10
10
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
10
0
0
10
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
10
% D
% Glu:
0
0
10
0
0
0
0
0
0
0
0
10
0
0
0
% E
% Phe:
0
37
0
10
0
0
10
0
0
0
0
0
0
10
10
% F
% Gly:
0
0
0
0
0
0
55
0
0
0
0
0
0
10
0
% G
% His:
0
0
0
10
0
55
0
10
0
10
10
0
0
0
0
% H
% Ile:
19
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
10
0
0
0
46
0
0
0
% K
% Leu:
64
19
0
0
73
10
10
10
46
10
0
0
10
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
19
0
0
0
10
10
0
10
0
0
0
0
0
% N
% Pro:
0
0
0
10
0
0
0
0
0
0
55
10
55
46
0
% P
% Gln:
0
10
0
0
0
19
0
0
0
0
0
10
0
10
10
% Q
% Arg:
0
10
0
10
0
0
0
0
10
37
0
0
0
0
55
% R
% Ser:
0
0
37
0
0
0
10
0
0
10
0
0
10
10
10
% S
% Thr:
0
0
10
10
10
0
0
10
10
0
19
0
10
0
0
% T
% Val:
10
0
0
0
10
0
0
0
10
10
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
46
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _