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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HES7
All Species:
20.3
Human Site:
S181
Identified Species:
44.67
UniProt:
Q9BYE0
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BYE0
NP_115969.2
225
24894
S181
A
W
S
P
S
L
C
S
P
R
A
G
D
S
G
Chimpanzee
Pan troglodytes
XP_001167471
225
24844
S181
A
W
S
P
T
L
C
S
P
R
A
G
D
S
G
Rhesus Macaque
Macaca mulatta
XP_001118139
272
29941
S228
A
W
S
P
S
L
C
S
P
R
A
G
D
S
G
Dog
Lupus familis
XP_850055
65
7913
D45
L
L
L
E
R
T
R
D
Q
N
L
R
N
P
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8BKT2
225
24871
S181
A
W
S
P
S
H
C
S
S
R
A
G
D
S
G
Rat
Rattus norvegicus
Q03062
166
18434
S145
A
P
Q
P
A
R
S
S
T
K
A
A
A
S
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509464
376
41515
T258
A
H
A
A
S
R
P
T
A
N
A
A
A
A
G
Chicken
Gallus gallus
O57337
290
31053
K189
G
A
V
P
V
P
C
K
L
E
P
T
E
A
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6QB00
270
30843
S226
S
W
H
S
S
T
R
S
P
T
L
A
Y
P
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q26263
435
46532
A370
S
G
S
L
N
L
S
A
G
S
H
D
S
S
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001001768
400
42683
S308
S
P
T
M
S
P
A
S
L
G
P
V
S
A
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
81.2
27.1
N.A.
92
32.4
N.A.
36.4
25.8
N.A.
21.4
N.A.
22.7
N.A.
N.A.
24.7
Protein Similarity:
100
99.1
81.6
27.1
N.A.
94.2
41.3
N.A.
43.3
39.6
N.A.
33.3
N.A.
34
N.A.
N.A.
33.2
P-Site Identity:
100
93.3
100
0
N.A.
86.6
33.3
N.A.
26.6
13.3
N.A.
26.6
N.A.
26.6
N.A.
N.A.
13.3
P-Site Similarity:
100
100
100
6.6
N.A.
86.6
46.6
N.A.
46.6
26.6
N.A.
33.3
N.A.
46.6
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
55
10
10
10
10
0
10
10
10
0
55
28
19
28
10
% A
% Cys:
0
0
0
0
0
0
46
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
10
0
0
0
10
37
0
0
% D
% Glu:
0
0
0
10
0
0
0
0
0
10
0
0
10
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
10
0
0
0
0
0
0
10
10
0
37
0
0
55
% G
% His:
0
10
10
0
0
10
0
0
0
0
10
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
10
0
10
0
0
0
0
10
% K
% Leu:
10
10
10
10
0
37
0
0
19
0
19
0
0
0
10
% L
% Met:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
10
0
0
0
0
19
0
0
10
0
0
% N
% Pro:
0
19
0
55
0
19
10
0
37
0
19
0
0
19
0
% P
% Gln:
0
0
10
0
0
0
0
0
10
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
10
19
19
0
0
37
0
10
0
0
0
% R
% Ser:
28
0
46
10
55
0
19
64
10
10
0
0
19
55
0
% S
% Thr:
0
0
10
0
10
19
0
10
10
10
0
10
0
0
0
% T
% Val:
0
0
10
0
10
0
0
0
0
0
0
10
0
0
10
% V
% Trp:
0
46
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _