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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RSPO3
All Species:
20
Human Site:
S241
Identified Species:
44
UniProt:
Q9BXY4
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.4
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BXY4
NP_116173.2
272
30929
S241
D
S
K
S
L
E
S
S
K
E
I
P
E
Q
R
Chimpanzee
Pan troglodytes
XP_001166327
272
30938
S241
D
S
K
S
L
E
S
S
K
E
I
P
E
Q
R
Rhesus Macaque
Macaca mulatta
XP_001106900
273
31121
S241
D
S
K
G
L
E
S
S
K
E
T
P
E
Q
R
Dog
Lupus familis
XP_533492
295
32962
S261
D
N
K
G
L
E
P
S
R
E
T
P
E
P
R
Cat
Felis silvestris
Mouse
Mus musculus
Q2TJ95
277
31436
S243
D
S
K
G
L
E
S
S
I
E
T
P
D
Q
Q
Rat
Rattus norvegicus
NP_001094460
276
31367
S242
D
S
K
G
L
E
S
S
R
E
T
S
E
Q
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506087
317
36007
R283
E
L
K
G
Q
E
P
R
R
E
S
L
D
Q
R
Chicken
Gallus gallus
XP_419752
275
31289
R241
E
S
K
G
R
A
A
R
R
Q
N
R
E
Q
R
Frog
Xenopus laevis
Q5UE90
243
27861
K221
D
K
R
N
K
K
K
K
K
K
L
L
E
R
A
Zebra Danio
Brachydanio rerio
Q5R328
317
35924
R279
E
K
V
T
A
E
A
R
R
E
R
K
R
E
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796266
368
40098
S290
I
S
C
P
L
P
A
S
P
A
N
G
Y
V
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
97
78.9
N.A.
87.7
86.2
N.A.
64.9
77
42.2
43.2
N.A.
N.A.
N.A.
N.A.
25.5
Protein Similarity:
100
99.6
98.1
84.7
N.A.
91.6
92
N.A.
73.8
84.3
57.7
62.1
N.A.
N.A.
N.A.
N.A.
39.9
P-Site Identity:
100
100
86.6
60
N.A.
66.6
66.6
N.A.
33.3
33.3
20
20
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
100
86.6
73.3
N.A.
80
73.3
N.A.
53.3
60
60
53.3
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
10
28
0
0
10
0
0
0
0
10
% A
% Cys:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
64
0
0
0
0
0
0
0
0
0
0
0
19
0
0
% D
% Glu:
28
0
0
0
0
73
0
0
0
73
0
0
64
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
55
0
0
0
0
0
0
0
10
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% H
% Ile:
10
0
0
0
0
0
0
0
10
0
19
0
0
0
0
% I
% Lys:
0
19
73
0
10
10
10
10
37
10
0
10
0
0
0
% K
% Leu:
0
10
0
0
64
0
0
0
0
0
10
19
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
10
0
0
0
0
0
0
19
0
0
0
0
% N
% Pro:
0
0
0
10
0
10
19
0
10
0
0
46
0
10
0
% P
% Gln:
0
0
0
0
10
0
0
0
0
10
0
0
0
64
10
% Q
% Arg:
0
0
10
0
10
0
0
28
46
0
10
10
10
10
64
% R
% Ser:
0
64
0
19
0
0
46
64
0
0
10
10
0
0
0
% S
% Thr:
0
0
0
10
0
0
0
0
0
0
37
0
0
0
10
% T
% Val:
0
0
10
0
0
0
0
0
0
0
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _