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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC12A9 All Species: 21.82
Human Site: S575 Identified Species: 43.64
UniProt: Q9BXP2 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BXP2 NP_064631.2 914 96110 S575 G D L D S L P S D P V Q P Q Y
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001105778 914 96183 S575 G D L D S L P S D P V Q P Q Y
Dog Lupus familis XP_546947 916 96148 S575 G D L D C L P S D P V Q P Q Y
Cat Felis silvestris
Mouse Mus musculus Q99MR3 914 96295 S575 G D L D S L P S D P V Q P Q Y
Rat Rattus norvegicus Q66HR0 914 95986 S575 G D L D S L P S D P V Q P Q Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis Q0VGW6 899 98326 S578 G D L D T L P S D P V Q T H Y
Zebra Danio Brachydanio rerio A2BFP5 899 98457 A581 G D L D V L P A D P V Q P Q Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_609887 941 104229 G603 V K L G D F K G I E D A E D N
Honey Bee Apis mellifera XP_395129 948 104316 I606 G E F L G Q N I D P T I E E Y
Nematode Worm Caenorhab. elegans Q09573 1020 112280 R676 D S Q K D K N R A R D V K T T
Sea Urchin Strong. purpuratus XP_791143 838 92404 Q520 E C P Y D P V Q Q E Y P A W L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P38329 1120 123980 L583 T A D F P K Q L N E L K T Q Q
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 98.8 93.4 N.A. 93.4 93.8 N.A. N.A. N.A. 61 58.3 N.A. 41.9 42.5 21 41.7
Protein Similarity: 100 N.A. 99 95.7 N.A. 95.7 96.1 N.A. N.A. N.A. 73.9 71.4 N.A. 58.8 58.8 36.8 58.4
P-Site Identity: 100 N.A. 100 93.3 N.A. 100 100 N.A. N.A. N.A. 80 86.6 N.A. 6.6 26.6 0 0
P-Site Similarity: 100 N.A. 100 93.3 N.A. 100 100 N.A. N.A. N.A. 86.6 93.3 N.A. 6.6 40 0 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. 28.9 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 47.3 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 0 0 0 0 0 9 9 0 0 9 9 0 0 % A
% Cys: 0 9 0 0 9 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 9 59 9 59 25 0 0 0 67 0 17 0 0 9 0 % D
% Glu: 9 9 0 0 0 0 0 0 0 25 0 0 17 9 0 % E
% Phe: 0 0 9 9 0 9 0 0 0 0 0 0 0 0 0 % F
% Gly: 67 0 0 9 9 0 0 9 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % H
% Ile: 0 0 0 0 0 0 0 9 9 0 0 9 0 0 0 % I
% Lys: 0 9 0 9 0 17 9 0 0 0 0 9 9 0 0 % K
% Leu: 0 0 67 9 0 59 0 9 0 0 9 0 0 0 9 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 17 0 9 0 0 0 0 0 9 % N
% Pro: 0 0 9 0 9 9 59 0 0 67 0 9 50 0 0 % P
% Gln: 0 0 9 0 0 9 9 9 9 0 0 59 0 59 9 % Q
% Arg: 0 0 0 0 0 0 0 9 0 9 0 0 0 0 0 % R
% Ser: 0 9 0 0 34 0 0 50 0 0 0 0 0 0 0 % S
% Thr: 9 0 0 0 9 0 0 0 0 0 9 0 17 9 9 % T
% Val: 9 0 0 0 9 0 9 0 0 0 59 9 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % W
% Tyr: 0 0 0 9 0 0 0 0 0 0 9 0 0 0 67 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _