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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PINK1
All Species:
9.7
Human Site:
Y404
Identified Species:
21.33
UniProt:
Q9BXM7
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BXM7
NP_115785.1
581
62769
Y404
Q
L
P
F
S
S
W
Y
V
D
R
G
G
N
G
Chimpanzee
Pan troglodytes
XP_001164912
491
52307
V325
E
L
V
P
A
S
R
V
A
L
A
G
E
Y
G
Rhesus Macaque
Macaca mulatta
XP_001096957
581
63018
Y404
Q
L
P
F
S
S
W
Y
V
D
R
G
G
N
G
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q99MQ3
580
63162
S403
R
L
P
F
N
S
S
S
V
E
R
G
G
N
G
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517392
268
28900
I105
A
I
K
M
M
W
N
I
S
S
R
G
R
G
T
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001008628
574
63728
W391
K
L
P
F
S
S
W
W
V
N
R
G
G
N
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572340
721
80209
D521
R
L
P
Y
V
S
H
D
V
D
K
G
G
N
A
Honey Bee
Apis mellifera
XP_623327
614
69709
D404
Y
L
P
Y
N
T
H
D
I
D
K
G
G
N
V
Nematode Worm
Caenorhab. elegans
Q09298
641
73035
E379
Q
V
D
Y
E
S
D
E
V
S
L
G
G
N
A
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39030
471
53019
S294
E
F
E
E
N
T
R
S
N
S
M
C
G
T
T
Baker's Yeast
Sacchar. cerevisiae
P24719
497
56831
R324
D
L
N
S
N
K
E
R
M
H
T
V
V
G
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
67.8
97.2
N.A.
N.A.
81.4
N.A.
N.A.
21
N.A.
N.A.
54.5
N.A.
28.8
34
27.6
N.A.
Protein Similarity:
100
69.5
97.9
N.A.
N.A.
87.4
N.A.
N.A.
30.6
N.A.
N.A.
67.3
N.A.
43
50.4
42.9
N.A.
P-Site Identity:
100
26.6
100
N.A.
N.A.
66.6
N.A.
N.A.
13.3
N.A.
N.A.
73.3
N.A.
53.3
40
40
N.A.
P-Site Similarity:
100
40
100
N.A.
N.A.
86.6
N.A.
N.A.
20
N.A.
N.A.
93.3
N.A.
73.3
73.3
53.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.5
20.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
37.3
35.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
10
0
0
0
10
0
10
0
0
0
19
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% C
% Asp:
10
0
10
0
0
0
10
19
0
37
0
0
0
0
0
% D
% Glu:
19
0
10
10
10
0
10
10
0
10
0
0
10
0
0
% E
% Phe:
0
10
0
37
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
82
73
19
37
% G
% His:
0
0
0
0
0
0
19
0
0
10
0
0
0
0
0
% H
% Ile:
0
10
0
0
0
0
0
10
10
0
0
0
0
0
0
% I
% Lys:
10
0
10
0
0
10
0
0
0
0
19
0
0
0
0
% K
% Leu:
0
73
0
0
0
0
0
0
0
10
10
0
0
0
0
% L
% Met:
0
0
0
10
10
0
0
0
10
0
10
0
0
0
0
% M
% Asn:
0
0
10
0
37
0
10
0
10
10
0
0
0
64
0
% N
% Pro:
0
0
55
10
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
28
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
19
0
0
0
0
0
19
10
0
0
46
0
10
0
0
% R
% Ser:
0
0
0
10
28
64
10
19
10
28
0
0
0
0
10
% S
% Thr:
0
0
0
0
0
19
0
0
0
0
10
0
0
10
28
% T
% Val:
0
10
10
0
10
0
0
10
55
0
0
10
10
0
10
% V
% Trp:
0
0
0
0
0
10
28
10
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
28
0
0
0
19
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _