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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PINK1
All Species:
11.82
Human Site:
T236
Identified Species:
26
UniProt:
Q9BXM7
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BXM7
NP_115785.1
581
62769
T236
S
S
E
A
I
L
N
T
M
S
Q
E
L
V
P
Chimpanzee
Pan troglodytes
XP_001164912
491
52307
A167
Q
R
Q
F
V
V
R
A
W
G
C
A
G
P
C
Rhesus Macaque
Macaca mulatta
XP_001096957
581
63018
T236
S
S
E
A
I
L
N
T
M
S
Q
E
L
V
P
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q99MQ3
580
63162
K235
S
S
E
A
I
L
S
K
M
S
Q
E
L
V
P
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517392
268
28900
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001008628
574
63728
S223
S
S
D
A
I
L
R
S
M
S
M
E
L
V
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572340
721
80209
A354
N
A
L
S
I
L
R
A
M
Y
K
E
T
V
P
Honey Bee
Apis mellifera
XP_623327
614
69709
S235
N
A
L
S
I
L
R
S
M
Y
R
E
T
I
P
Nematode Worm
Caenorhab. elegans
Q09298
641
73035
K216
D
G
D
A
H
L
L
K
S
M
G
N
E
L
A
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39030
471
53019
V157
A
F
G
K
V
Y
Q
V
R
K
K
D
T
S
E
Baker's Yeast
Sacchar. cerevisiae
P24719
497
56831
N170
I
T
N
R
I
V
G
N
G
T
F
G
H
V
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
67.8
97.2
N.A.
N.A.
81.4
N.A.
N.A.
21
N.A.
N.A.
54.5
N.A.
28.8
34
27.6
N.A.
Protein Similarity:
100
69.5
97.9
N.A.
N.A.
87.4
N.A.
N.A.
30.6
N.A.
N.A.
67.3
N.A.
43
50.4
42.9
N.A.
P-Site Identity:
100
0
100
N.A.
N.A.
86.6
N.A.
N.A.
0
N.A.
N.A.
73.3
N.A.
40
33.3
13.3
N.A.
P-Site Similarity:
100
20
100
N.A.
N.A.
93.3
N.A.
N.A.
0
N.A.
N.A.
86.6
N.A.
66.6
73.3
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.5
20.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
37.3
35.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
19
0
46
0
0
0
19
0
0
0
10
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
10
% C
% Asp:
10
0
19
0
0
0
0
0
0
0
0
10
0
0
0
% D
% Glu:
0
0
28
0
0
0
0
0
0
0
0
55
10
0
10
% E
% Phe:
0
10
0
10
0
0
0
0
0
0
10
0
0
0
0
% F
% Gly:
0
10
10
0
0
0
10
0
10
10
10
10
10
0
0
% G
% His:
0
0
0
0
10
0
0
0
0
0
0
0
10
0
0
% H
% Ile:
10
0
0
0
64
0
0
0
0
0
0
0
0
10
0
% I
% Lys:
0
0
0
10
0
0
0
19
0
10
19
0
0
0
0
% K
% Leu:
0
0
19
0
0
64
10
0
0
0
0
0
37
10
10
% L
% Met:
0
0
0
0
0
0
0
0
55
10
10
0
0
0
0
% M
% Asn:
19
0
10
0
0
0
19
10
0
0
0
10
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
55
% P
% Gln:
10
0
10
0
0
0
10
0
0
0
28
0
0
0
0
% Q
% Arg:
0
10
0
10
0
0
37
0
10
0
10
0
0
0
0
% R
% Ser:
37
37
0
19
0
0
10
19
10
37
0
0
0
10
0
% S
% Thr:
0
10
0
0
0
0
0
19
0
10
0
0
28
0
0
% T
% Val:
0
0
0
0
19
19
0
10
0
0
0
0
0
55
0
% V
% Trp:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
0
0
0
19
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _