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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CDCA4 All Species: 18.48
Human Site: S222 Identified Species: 50.83
UniProt: Q9BXL8 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BXL8 NP_060425.2 241 26114 S222 P A T P G P S S S C K S D L G
Chimpanzee Pan troglodytes XP_510205 241 26065 S222 P A T P G P S S S C K S D L G
Rhesus Macaque Macaca mulatta XP_001096509 166 17617 S148 A T P G P S A S C K S D L G E
Dog Lupus familis XP_855522 242 25885 S223 A A T P P P G S S C R S D L G
Cat Felis silvestris
Mouse Mus musculus Q9CWM2 237 26089 S218 A A T P P P S S T C K S D L A
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507850 246 27592 S227 P P T T N S S S N C K S D L N
Chicken Gallus gallus NP_001026383 249 28005 S230 P T T T T S S S N C K S D L N
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001008580 286 31346 P267 S P S I V S T P N C R S D L N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783091 346 37757 G322 S T T G A Q G G S C R S D L M
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 65.9 73.5 N.A. 73.4 N.A. N.A. 64.2 62.2 N.A. 44.4 N.A. N.A. N.A. N.A. 28.6
Protein Similarity: 100 99.5 67.2 78 N.A. 78 N.A. N.A. 74.8 75 N.A. 58.7 N.A. N.A. N.A. N.A. 39.8
P-Site Identity: 100 100 6.6 73.3 N.A. 73.3 N.A. N.A. 60 60 N.A. 26.6 N.A. N.A. N.A. N.A. 40
P-Site Similarity: 100 100 13.3 80 N.A. 80 N.A. N.A. 66.6 66.6 N.A. 53.3 N.A. N.A. N.A. N.A. 46.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 34 45 0 0 12 0 12 0 0 0 0 0 0 0 12 % A
% Cys: 0 0 0 0 0 0 0 0 12 89 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 12 89 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 23 23 0 23 12 0 0 0 0 0 12 34 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 12 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 12 56 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 12 89 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12 % M
% Asn: 0 0 0 0 12 0 0 0 34 0 0 0 0 0 34 % N
% Pro: 45 23 12 45 34 45 0 12 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 12 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 34 0 0 0 0 % R
% Ser: 23 0 12 0 0 45 56 78 45 0 12 89 0 0 0 % S
% Thr: 0 34 78 23 12 0 12 0 12 0 0 0 0 0 0 % T
% Val: 0 0 0 0 12 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _