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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GPR174
All Species:
8.79
Human Site:
S263
Identified Species:
21.48
UniProt:
Q9BXC1
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BXC1
NP_115942.1
333
38503
S263
V
K
S
N
E
I
K
S
C
L
A
R
R
V
I
Chimpanzee
Pan troglodytes
XP_521150
370
41849
N282
V
R
S
Q
A
I
T
N
C
F
L
E
R
F
A
Rhesus Macaque
Macaca mulatta
XP_001102084
333
38347
S263
V
K
S
N
E
I
K
S
C
L
A
R
R
V
I
Dog
Lupus familis
XP_549100
388
44295
K319
F
I
F
Y
T
M
V
K
E
T
I
I
S
S
C
Cat
Felis silvestris
Mouse
Mus musculus
Q3U507
335
38742
S263
V
K
S
N
E
I
K
S
C
F
A
R
R
V
I
Rat
Rattus norvegicus
Q4G072
344
39312
N262
V
R
T
Q
T
F
V
N
C
S
V
G
A
A
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520859
369
40361
G296
V
K
A
N
K
I
D
G
C
L
A
R
R
L
I
Chicken
Gallus gallus
P32250
308
35579
F239
L
V
I
F
C
F
C
F
V
P
Y
N
I
T
L
Frog
Xenopus laevis
P79928
537
62006
K288
Y
A
R
L
L
G
I
K
C
Y
A
L
N
V
I
Zebra Danio
Brachydanio rerio
A5PLE7
368
41686
D274
K
K
L
R
Y
D
P
D
C
S
E
L
H
K
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
31.3
98.1
41.7
N.A.
87.7
29.9
N.A.
61.2
29.7
21.2
28.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
49.4
98.8
57.7
N.A.
94
50.5
N.A.
75.3
52.2
35.7
49.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
33.3
100
0
N.A.
93.3
13.3
N.A.
66.6
0
26.6
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
46.6
100
6.6
N.A.
93.3
40
N.A.
86.6
13.3
26.6
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
10
0
10
0
0
0
0
0
50
0
10
10
10
% A
% Cys:
0
0
0
0
10
0
10
0
80
0
0
0
0
0
10
% C
% Asp:
0
0
0
0
0
10
10
10
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
30
0
0
0
10
0
10
10
0
0
0
% E
% Phe:
10
0
10
10
0
20
0
10
0
20
0
0
0
10
10
% F
% Gly:
0
0
0
0
0
10
0
10
0
0
0
10
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% H
% Ile:
0
10
10
0
0
50
10
0
0
0
10
10
10
0
50
% I
% Lys:
10
50
0
0
10
0
30
20
0
0
0
0
0
10
0
% K
% Leu:
10
0
10
10
10
0
0
0
0
30
10
20
0
10
10
% L
% Met:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
40
0
0
0
20
0
0
0
10
10
0
0
% N
% Pro:
0
0
0
0
0
0
10
0
0
10
0
0
0
0
0
% P
% Gln:
0
0
0
20
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
20
10
10
0
0
0
0
0
0
0
40
50
0
0
% R
% Ser:
0
0
40
0
0
0
0
30
0
20
0
0
10
10
0
% S
% Thr:
0
0
10
0
20
0
10
0
0
10
0
0
0
10
0
% T
% Val:
60
10
0
0
0
0
20
0
10
0
10
0
0
40
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
10
10
0
0
0
0
10
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _