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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CARD10
All Species:
13.94
Human Site:
S549
Identified Species:
38.33
UniProt:
Q9BWT7
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BWT7
NP_055365.2
1032
115931
S549
P
P
K
R
S
F
S
S
M
S
D
I
T
G
S
Chimpanzee
Pan troglodytes
XP_515116
1033
115970
S549
P
P
K
R
S
F
S
S
M
S
D
I
T
G
S
Rhesus Macaque
Macaca mulatta
XP_001104636
1259
144246
S661
T
K
M
Q
P
P
R
S
R
S
S
I
M
S
I
Dog
Lupus familis
XP_538389
1029
115309
S545
P
P
K
R
S
F
S
S
M
S
D
I
T
G
S
Cat
Felis silvestris
Mouse
Mus musculus
P58660
1021
114396
S542
K
R
S
F
S
S
M
S
D
I
T
G
S
V
T
Rat
Rattus norvegicus
Q9EPY0
536
62613
F143
L
L
S
S
K
D
D
F
I
K
E
L
R
V
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510375
817
92558
R424
L
V
E
K
D
Q
Y
R
K
Q
V
R
G
L
E
Chicken
Gallus gallus
XP_416277
991
113701
S574
L
S
C
G
S
F
S
S
M
E
D
T
A
G
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_685144
1357
154601
A810
S
F
L
P
S
D
T
A
D
T
D
S
G
D
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.6
32.5
92.6
N.A.
90.5
25
N.A.
58.4
54.8
N.A.
29.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
98
47.5
94.4
N.A.
93.2
36.4
N.A.
64.5
67.8
N.A.
44.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
20
100
N.A.
13.3
0
N.A.
0
46.6
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
26.6
100
N.A.
26.6
20
N.A.
13.3
53.3
N.A.
40
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
12
0
0
0
0
12
0
0
% A
% Cys:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
12
23
12
0
23
0
56
0
0
12
0
% D
% Glu:
0
0
12
0
0
0
0
0
0
12
12
0
0
0
12
% E
% Phe:
0
12
0
12
0
45
0
12
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
12
0
0
0
0
0
0
0
12
23
45
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
12
12
0
45
0
0
12
% I
% Lys:
12
12
34
12
12
0
0
0
12
12
0
0
0
0
12
% K
% Leu:
34
12
12
0
0
0
0
0
0
0
0
12
0
12
0
% L
% Met:
0
0
12
0
0
0
12
0
45
0
0
0
12
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
23
% N
% Pro:
34
34
0
12
12
12
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
12
0
12
0
0
0
12
0
0
0
0
0
% Q
% Arg:
0
12
0
34
0
0
12
12
12
0
0
12
12
0
0
% R
% Ser:
12
12
23
12
67
12
45
67
0
45
12
12
12
12
34
% S
% Thr:
12
0
0
0
0
0
12
0
0
12
12
12
34
0
12
% T
% Val:
0
12
0
0
0
0
0
0
0
0
12
0
0
23
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _