KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPAP1
All Species:
29.7
Human Site:
T374
Identified Species:
59.39
UniProt:
Q9BWH6
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BWH6
NP_056355.2
1393
152755
T374
A
P
D
V
D
L
P
T
H
L
G
L
H
H
H
Chimpanzee
Pan troglodytes
XP_510325
1393
152620
T374
A
P
D
A
D
L
P
T
H
L
G
L
H
H
H
Rhesus Macaque
Macaca mulatta
XP_001101155
1393
152679
T374
A
P
D
V
D
L
P
T
H
L
G
L
H
H
H
Dog
Lupus familis
XP_544632
1394
153681
T374
A
P
D
V
D
L
P
T
H
L
G
L
H
H
H
Cat
Felis silvestris
Mouse
Mus musculus
Q80TE0
1409
155251
T390
A
P
D
V
D
L
P
T
H
L
G
L
H
H
H
Rat
Rattus norvegicus
Q3T1I9
1400
154741
T382
E
P
D
V
D
L
P
T
H
L
G
L
H
H
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_421141
1325
148827
T374
P
A
D
A
D
L
P
T
H
L
G
L
H
H
H
Frog
Xenopus laevis
NP_001084769
1421
158210
T376
P
P
N
S
E
I
P
T
H
M
G
L
H
H
H
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648573
1215
137437
L280
G
N
P
A
I
E
L
L
Q
E
S
D
K
G
N
Honey Bee
Apis mellifera
XP_624143
1030
118532
D95
L
K
Q
M
S
Q
E
D
I
L
K
E
K
S
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793628
1457
162231
V414
A
R
D
A
L
V
S
V
R
E
G
L
F
H
H
Poplar Tree
Populus trichocarpa
XP_002312932
1530
171565
N374
A
D
E
P
D
T
G
N
I
S
S
D
N
G
L
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
95.9
84.2
N.A.
79.2
79.7
N.A.
N.A.
53.1
49
N.A.
N.A.
23.3
24.7
N.A.
34.7
Protein Similarity:
100
99.5
97.4
89.4
N.A.
85.8
86.4
N.A.
N.A.
67.6
64.5
N.A.
N.A.
36.6
39.4
N.A.
51.3
P-Site Identity:
100
93.3
100
100
N.A.
100
93.3
N.A.
N.A.
80
60
N.A.
N.A.
0
6.6
N.A.
40
P-Site Similarity:
100
93.3
100
100
N.A.
100
93.3
N.A.
N.A.
80
86.6
N.A.
N.A.
6.6
13.3
N.A.
46.6
Percent
Protein Identity:
20.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
37.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
59
9
0
34
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
67
0
67
0
0
9
0
0
0
17
0
0
0
% D
% Glu:
9
0
9
0
9
9
9
0
0
17
0
9
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% F
% Gly:
9
0
0
0
0
0
9
0
0
0
75
0
0
17
0
% G
% His:
0
0
0
0
0
0
0
0
67
0
0
0
67
75
75
% H
% Ile:
0
0
0
0
9
9
0
0
17
0
0
0
0
0
0
% I
% Lys:
0
9
0
0
0
0
0
0
0
0
9
0
17
0
9
% K
% Leu:
9
0
0
0
9
59
9
9
0
67
0
75
0
0
9
% L
% Met:
0
0
0
9
0
0
0
0
0
9
0
0
0
0
0
% M
% Asn:
0
9
9
0
0
0
0
9
0
0
0
0
9
0
9
% N
% Pro:
17
59
9
9
0
0
67
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
9
0
0
9
0
0
9
0
0
0
0
0
0
% Q
% Arg:
0
9
0
0
0
0
0
0
9
0
0
0
0
0
0
% R
% Ser:
0
0
0
9
9
0
9
0
0
9
17
0
0
9
0
% S
% Thr:
0
0
0
0
0
9
0
67
0
0
0
0
0
0
0
% T
% Val:
0
0
0
42
0
9
0
9
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _