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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPAP1
All Species:
18.18
Human Site:
T290
Identified Species:
36.36
UniProt:
Q9BWH6
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BWH6
NP_056355.2
1393
152755
T290
G
G
P
S
A
N
V
T
K
E
E
P
L
M
S
Chimpanzee
Pan troglodytes
XP_510325
1393
152620
T290
G
G
P
S
A
N
V
T
K
E
E
P
L
M
S
Rhesus Macaque
Macaca mulatta
XP_001101155
1393
152679
T290
G
G
P
S
A
N
V
T
K
E
K
P
L
M
S
Dog
Lupus familis
XP_544632
1394
153681
T290
G
G
H
S
V
E
V
T
G
E
E
L
I
V
P
Cat
Felis silvestris
Mouse
Mus musculus
Q80TE0
1409
155251
T290
K
R
P
S
V
L
V
T
K
E
E
P
V
T
S
Rat
Rattus norvegicus
Q3T1I9
1400
154741
S290
E
R
P
S
V
P
V
S
K
E
E
P
I
M
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_421141
1325
148827
R291
E
I
K
M
E
Q
N
R
P
E
E
A
H
A
N
Frog
Xenopus laevis
NP_001084769
1421
158210
E292
E
P
Q
T
V
H
L
E
E
P
Q
Y
L
S
E
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648573
1215
137437
V201
L
H
Q
E
N
L
N
V
L
K
Q
M
N
E
Q
Honey Bee
Apis mellifera
XP_624143
1030
118532
E16
R
P
K
P
T
D
S
E
E
E
L
F
R
F
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793628
1457
162231
M306
M
S
E
P
V
S
V
M
S
P
S
T
Q
R
V
Poplar Tree
Populus trichocarpa
XP_002312932
1530
171565
P293
S
S
Q
V
D
S
I
P
I
E
N
R
L
I
K
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
95.9
84.2
N.A.
79.2
79.7
N.A.
N.A.
53.1
49
N.A.
N.A.
23.3
24.7
N.A.
34.7
Protein Similarity:
100
99.5
97.4
89.4
N.A.
85.8
86.4
N.A.
N.A.
67.6
64.5
N.A.
N.A.
36.6
39.4
N.A.
51.3
P-Site Identity:
100
100
93.3
46.6
N.A.
60
60
N.A.
N.A.
13.3
6.6
N.A.
N.A.
0
6.6
N.A.
6.6
P-Site Similarity:
100
100
100
60
N.A.
66.6
73.3
N.A.
N.A.
20
40
N.A.
N.A.
13.3
20
N.A.
13.3
Percent
Protein Identity:
20.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
37.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
25
0
0
0
0
0
0
9
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
9
9
0
0
0
0
0
0
0
0
0
% D
% Glu:
25
0
9
9
9
9
0
17
17
75
50
0
0
9
9
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
9
0
9
0
% F
% Gly:
34
34
0
0
0
0
0
0
9
0
0
0
0
0
0
% G
% His:
0
9
9
0
0
9
0
0
0
0
0
0
9
0
0
% H
% Ile:
0
9
0
0
0
0
9
0
9
0
0
0
17
9
0
% I
% Lys:
9
0
17
0
0
0
0
0
42
9
9
0
0
0
9
% K
% Leu:
9
0
0
0
0
17
9
0
9
0
9
9
42
0
0
% L
% Met:
9
0
0
9
0
0
0
9
0
0
0
9
0
34
0
% M
% Asn:
0
0
0
0
9
25
17
0
0
0
9
0
9
0
9
% N
% Pro:
0
17
42
17
0
9
0
9
9
17
0
42
0
0
17
% P
% Gln:
0
0
25
0
0
9
0
0
0
0
17
0
9
0
9
% Q
% Arg:
9
17
0
0
0
0
0
9
0
0
0
9
9
9
0
% R
% Ser:
9
17
0
50
0
17
9
9
9
0
9
0
0
9
42
% S
% Thr:
0
0
0
9
9
0
0
42
0
0
0
9
0
9
0
% T
% Val:
0
0
0
9
42
0
59
9
0
0
0
0
9
9
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _