Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RPAP1 All Species: 18.79
Human Site: S519 Identified Species: 37.58
UniProt: Q9BWH6 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BWH6 NP_056355.2 1393 152755 S519 A G K A K R K S P E E E S R P
Chimpanzee Pan troglodytes XP_510325 1393 152620 S519 A G N A K R K S P E E E S R P
Rhesus Macaque Macaca mulatta XP_001101155 1393 152679 S519 A E K A K R K S P E E E S R P
Dog Lupus familis XP_544632 1394 153681 S520 A E K A K R K S P E K G N Q P
Cat Felis silvestris
Mouse Mus musculus Q80TE0 1409 155251 T535 T E K V K R K T P E E G S R P
Rat Rattus norvegicus Q3T1I9 1400 154741 T527 K E K V N R K T P E E G S R P
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_421141 1325 148827 A512 E E E E L T G A E K S Q N K N
Frog Xenopus laevis NP_001084769 1421 158210 K525 M G K E E R K K V K E E K K S
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_648573 1215 137437 F412 K I F F L L R F G L D D N A P
Honey Bee Apis mellifera XP_624143 1030 118532 Q227 K D D N I S M Q K G L H H H G
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_793628 1457 162231 E563 D E E E E E E E E Q K Q T K P
Poplar Tree Populus trichocarpa XP_002312932 1530 171565 F543 A G F L H G G F W K Y N A K P
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 95.9 84.2 N.A. 79.2 79.7 N.A. N.A. 53.1 49 N.A. N.A. 23.3 24.7 N.A. 34.7
Protein Similarity: 100 99.5 97.4 89.4 N.A. 85.8 86.4 N.A. N.A. 67.6 64.5 N.A. N.A. 36.6 39.4 N.A. 51.3
P-Site Identity: 100 93.3 93.3 66.6 N.A. 66.6 60 N.A. N.A. 0 40 N.A. N.A. 6.6 0 N.A. 6.6
P-Site Similarity: 100 93.3 93.3 86.6 N.A. 73.3 66.6 N.A. N.A. 40 60 N.A. N.A. 33.3 0 N.A. 60
Percent
Protein Identity: 20.2 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 37.3 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 20 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 40 N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 42 0 0 34 0 0 0 9 0 0 0 0 9 9 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 9 9 9 0 0 0 0 0 0 0 9 9 0 0 0 % D
% Glu: 9 50 17 25 17 9 9 9 17 50 50 34 0 0 0 % E
% Phe: 0 0 17 9 0 0 0 17 0 0 0 0 0 0 0 % F
% Gly: 0 34 0 0 0 9 17 0 9 9 0 25 0 0 9 % G
% His: 0 0 0 0 9 0 0 0 0 0 0 9 9 9 0 % H
% Ile: 0 9 0 0 9 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 25 0 50 0 42 0 59 9 9 25 17 0 9 34 0 % K
% Leu: 0 0 0 9 17 9 0 0 0 9 9 0 0 0 0 % L
% Met: 9 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 9 9 9 0 0 0 0 0 0 9 25 0 9 % N
% Pro: 0 0 0 0 0 0 0 0 50 0 0 0 0 0 75 % P
% Gln: 0 0 0 0 0 0 0 9 0 9 0 17 0 9 0 % Q
% Arg: 0 0 0 0 0 59 9 0 0 0 0 0 0 42 0 % R
% Ser: 0 0 0 0 0 9 0 34 0 0 9 0 42 0 9 % S
% Thr: 9 0 0 0 0 9 0 17 0 0 0 0 9 0 0 % T
% Val: 0 0 0 17 0 0 0 0 9 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _