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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPAP1
All Species:
36.06
Human Site:
S401
Identified Species:
72.12
UniProt:
Q9BWH6
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BWH6
NP_056355.2
1393
152755
S401
E
L
F
H
L
T
R
S
Q
V
S
Q
Q
R
A
Chimpanzee
Pan troglodytes
XP_510325
1393
152620
S401
E
L
F
H
L
T
R
S
Q
V
S
Q
Q
R
A
Rhesus Macaque
Macaca mulatta
XP_001101155
1393
152679
S401
E
L
F
H
L
T
R
S
Q
V
S
Q
Q
R
A
Dog
Lupus familis
XP_544632
1394
153681
S401
E
L
F
H
L
T
R
S
Q
V
S
Q
Q
R
A
Cat
Felis silvestris
Mouse
Mus musculus
Q80TE0
1409
155251
S417
E
L
F
H
L
T
R
S
Q
V
S
Q
Q
R
A
Rat
Rattus norvegicus
Q3T1I9
1400
154741
S409
E
L
F
H
L
T
R
S
Q
V
S
Q
Q
R
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_421141
1325
148827
S401
E
L
F
H
L
S
R
S
Q
L
I
Q
Q
R
T
Frog
Xenopus laevis
NP_001084769
1421
158210
S403
E
F
F
H
L
S
R
S
Q
F
I
Q
Q
R
T
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648573
1215
137437
P306
L
A
W
M
R
D
I
P
A
K
I
S
E
L
K
Honey Bee
Apis mellifera
XP_624143
1030
118532
K121
F
L
R
D
K
R
I
K
K
Q
K
I
N
K
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793628
1457
162231
S441
E
L
F
T
L
S
R
S
A
V
I
Q
Q
R
V
Poplar Tree
Populus trichocarpa
XP_002312932
1530
171565
S414
E
A
V
Q
L
T
R
S
V
I
P
G
Q
R
A
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
95.9
84.2
N.A.
79.2
79.7
N.A.
N.A.
53.1
49
N.A.
N.A.
23.3
24.7
N.A.
34.7
Protein Similarity:
100
99.5
97.4
89.4
N.A.
85.8
86.4
N.A.
N.A.
67.6
64.5
N.A.
N.A.
36.6
39.4
N.A.
51.3
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
73.3
66.6
N.A.
N.A.
0
6.6
N.A.
66.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
86.6
73.3
N.A.
N.A.
13.3
20
N.A.
73.3
Percent
Protein Identity:
20.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
37.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
60
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
17
0
0
0
0
0
0
17
0
0
0
0
0
59
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
9
0
9
0
0
0
0
0
0
0
0
0
% D
% Glu:
84
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% E
% Phe:
9
9
75
0
0
0
0
0
0
9
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% G
% His:
0
0
0
67
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
17
0
0
9
34
9
0
0
9
% I
% Lys:
0
0
0
0
9
0
0
9
9
9
9
0
0
9
9
% K
% Leu:
9
75
0
0
84
0
0
0
0
9
0
0
0
9
0
% L
% Met:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% N
% Pro:
0
0
0
0
0
0
0
9
0
0
9
0
0
0
0
% P
% Gln:
0
0
0
9
0
0
0
0
67
9
0
75
84
0
0
% Q
% Arg:
0
0
9
0
9
9
84
0
0
0
0
0
0
84
0
% R
% Ser:
0
0
0
0
0
25
0
84
0
0
50
9
0
0
0
% S
% Thr:
0
0
0
9
0
59
0
0
0
0
0
0
0
0
17
% T
% Val:
0
0
9
0
0
0
0
0
9
59
0
0
0
0
9
% V
% Trp:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _