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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPAP1
All Species:
21.52
Human Site:
S277
Identified Species:
43.03
UniProt:
Q9BWH6
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BWH6
NP_056355.2
1393
152755
S277
E
Q
T
G
E
T
A
S
E
E
Q
R
P
G
G
Chimpanzee
Pan troglodytes
XP_510325
1393
152620
S277
E
Q
T
G
E
T
A
S
E
E
Q
R
P
G
G
Rhesus Macaque
Macaca mulatta
XP_001101155
1393
152679
S277
E
Q
T
G
E
K
A
S
E
E
Q
R
P
G
G
Dog
Lupus familis
XP_544632
1394
153681
T277
E
Q
A
G
E
K
A
T
E
E
Q
R
P
G
G
Cat
Felis silvestris
Mouse
Mus musculus
Q80TE0
1409
155251
T277
E
Q
T
G
T
K
A
T
K
K
Q
S
P
K
R
Rat
Rattus norvegicus
Q3T1I9
1400
154741
T277
E
Q
T
E
T
K
A
T
K
E
Q
N
P
E
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_421141
1325
148827
N278
L
K
S
R
R
S
G
N
V
D
Q
K
N
E
I
Frog
Xenopus laevis
NP_001084769
1421
158210
S279
S
T
D
G
H
S
S
S
V
Q
A
S
Q
E
P
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648573
1215
137437
A188
T
S
S
I
I
K
D
A
K
L
G
K
E
L
H
Honey Bee
Apis mellifera
XP_624143
1030
118532
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793628
1457
162231
H293
A
Q
N
Q
N
S
S
H
Q
E
S
P
P
M
S
Poplar Tree
Populus trichocarpa
XP_002312932
1530
171565
S280
L
K
K
K
N
V
S
S
S
D
E
A
V
S
S
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
95.9
84.2
N.A.
79.2
79.7
N.A.
N.A.
53.1
49
N.A.
N.A.
23.3
24.7
N.A.
34.7
Protein Similarity:
100
99.5
97.4
89.4
N.A.
85.8
86.4
N.A.
N.A.
67.6
64.5
N.A.
N.A.
36.6
39.4
N.A.
51.3
P-Site Identity:
100
100
93.3
80
N.A.
46.6
46.6
N.A.
N.A.
6.6
13.3
N.A.
N.A.
0
0
N.A.
20
P-Site Similarity:
100
100
93.3
86.6
N.A.
66.6
60
N.A.
N.A.
46.6
33.3
N.A.
N.A.
26.6
0
N.A.
40
Percent
Protein Identity:
20.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
37.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
9
0
0
0
50
9
0
0
9
9
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
9
0
0
0
9
0
0
17
0
0
0
0
0
% D
% Glu:
50
0
0
9
34
0
0
0
34
50
9
0
9
25
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
50
0
0
9
0
0
0
9
0
0
34
34
% G
% His:
0
0
0
0
9
0
0
9
0
0
0
0
0
0
9
% H
% Ile:
0
0
0
9
9
0
0
0
0
0
0
0
0
0
9
% I
% Lys:
0
17
9
9
0
42
0
0
25
9
0
17
0
9
0
% K
% Leu:
17
0
0
0
0
0
0
0
0
9
0
0
0
9
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% M
% Asn:
0
0
9
0
17
0
0
9
0
0
0
9
9
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
9
59
0
9
% P
% Gln:
0
59
0
9
0
0
0
0
9
9
59
0
9
0
0
% Q
% Arg:
0
0
0
9
9
0
0
0
0
0
0
34
0
0
17
% R
% Ser:
9
9
17
0
0
25
25
42
9
0
9
17
0
9
17
% S
% Thr:
9
9
42
0
17
17
0
25
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
9
0
0
17
0
0
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _