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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPAP1
All Species:
19.09
Human Site:
S1383
Identified Species:
38.18
UniProt:
Q9BWH6
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BWH6
NP_056355.2
1393
152755
S1383
H
Y
L
Q
R
L
T
S
T
V
L
Q
N
G
V
Chimpanzee
Pan troglodytes
XP_510325
1393
152620
S1383
H
Y
L
Q
R
L
T
S
T
V
L
Q
N
G
V
Rhesus Macaque
Macaca mulatta
XP_001101155
1393
152679
S1383
H
Y
L
Q
R
L
T
S
T
V
L
Q
N
G
V
Dog
Lupus familis
XP_544632
1394
153681
S1384
Q
Y
L
Q
R
L
T
S
G
M
L
Q
N
G
L
Cat
Felis silvestris
Mouse
Mus musculus
Q80TE0
1409
155251
T1399
Q
C
L
Q
T
L
P
T
E
G
L
Q
N
G
G
Rat
Rattus norvegicus
Q3T1I9
1400
154741
T1390
Q
Y
L
Q
T
L
P
T
E
V
L
Q
N
G
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_421141
1325
148827
K1314
Y
L
Q
M
V
T
Q
K
E
N
K
E
N
A
P
Frog
Xenopus laevis
NP_001084769
1421
158210
K1412
Y
L
K
T
T
T
E
K
H
H
E
A
K
G
E
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648573
1215
137437
S1206
A
Q
H
H
F
N
H
S
K
S
V
H
K
A
T
Honey Bee
Apis mellifera
XP_624143
1030
118532
L1021
S
N
K
V
L
A
G
L
L
L
N
Y
Q
L
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793628
1457
162231
R1439
V
V
L
Q
A
A
E
R
A
I
Q
E
Q
R
S
Poplar Tree
Populus trichocarpa
XP_002312932
1530
171565
E1498
S
D
I
E
K
R
F
E
V
L
V
E
A
C
D
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
95.9
84.2
N.A.
79.2
79.7
N.A.
N.A.
53.1
49
N.A.
N.A.
23.3
24.7
N.A.
34.7
Protein Similarity:
100
99.5
97.4
89.4
N.A.
85.8
86.4
N.A.
N.A.
67.6
64.5
N.A.
N.A.
36.6
39.4
N.A.
51.3
P-Site Identity:
100
100
100
73.3
N.A.
46.6
60
N.A.
N.A.
6.6
6.6
N.A.
N.A.
6.6
0
N.A.
13.3
P-Site Similarity:
100
100
100
86.6
N.A.
53.3
66.6
N.A.
N.A.
20
13.3
N.A.
N.A.
13.3
6.6
N.A.
26.6
Percent
Protein Identity:
20.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
37.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
40
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
0
9
17
0
0
9
0
0
9
9
17
0
% A
% Cys:
0
9
0
0
0
0
0
0
0
0
0
0
0
9
0
% C
% Asp:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
9
% D
% Glu:
0
0
0
9
0
0
17
9
25
0
9
25
0
0
9
% E
% Phe:
0
0
0
0
9
0
9
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
9
0
9
9
0
0
0
59
17
% G
% His:
25
0
9
9
0
0
9
0
9
9
0
9
0
0
0
% H
% Ile:
0
0
9
0
0
0
0
0
0
9
0
0
0
0
0
% I
% Lys:
0
0
17
0
9
0
0
17
9
0
9
0
17
0
0
% K
% Leu:
0
17
59
0
9
50
0
9
9
17
50
0
0
9
9
% L
% Met:
0
0
0
9
0
0
0
0
0
9
0
0
0
0
0
% M
% Asn:
0
9
0
0
0
9
0
0
0
9
9
0
59
0
0
% N
% Pro:
0
0
0
0
0
0
17
0
0
0
0
0
0
0
17
% P
% Gln:
25
9
9
59
0
0
9
0
0
0
9
50
17
0
0
% Q
% Arg:
0
0
0
0
34
9
0
9
0
0
0
0
0
9
0
% R
% Ser:
17
0
0
0
0
0
0
42
0
9
0
0
0
0
9
% S
% Thr:
0
0
0
9
25
17
34
17
25
0
0
0
0
0
9
% T
% Val:
9
9
0
9
9
0
0
0
9
34
17
0
0
0
25
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
17
42
0
0
0
0
0
0
0
0
0
9
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _