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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HIGD2A All Species: 20.61
Human Site: S16 Identified Species: 37.78
UniProt: Q9BW72 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BW72 NP_620175.1 106 11529 S16 P E V P F E P S K P P V I E G
Chimpanzee Pan troglodytes XP_527130 106 11541 S16 Q E V P F E P S K P P V I E G
Rhesus Macaque Macaca mulatta XP_001084675 106 11638 S16 P E V P F E P S K P P V I E G
Dog Lupus familis XP_536423 106 11321 S16 P G A P F E P S Q P P V I E G
Cat Felis silvestris
Mouse Mus musculus Q9CQJ1 106 11350 S16 P E A P F D P S K P P V I E G
Rat Rattus norvegicus Q8VH49 93 10283
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514680 81 8548
Chicken Gallus gallus XP_414550 124 13681 P34 P R P Q P W R P G L P R P W S
Frog Xenopus laevis NP_001087828 93 10198
Zebra Danio Brachydanio rerio NP_001017641 116 12208 S26 P P V L L D L S Q P P V I E G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_573120 102 11395 E13 E V S L P E E E L D W I Q L R
Honey Bee Apis mellifera XP_001122466 103 11799 E14 E N S E E L K E L D W I R V Q
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780376 117 12675 Y22 E M R K S F Q Y P G D I P L E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99 90.5 81.1 N.A. 83 35.8 N.A. 47.1 48.3 56.5 53.4 N.A. 48.1 44.3 N.A. 46.1
Protein Similarity: 100 99 98.1 87.7 N.A. 87.7 51.8 N.A. 57.5 60.4 70.7 71.5 N.A. 65 61.3 N.A. 58.9
P-Site Identity: 100 93.3 100 80 N.A. 86.6 0 N.A. 0 13.3 0 60 N.A. 6.6 0 N.A. 0
P-Site Similarity: 100 93.3 100 86.6 N.A. 93.3 0 N.A. 0 13.3 0 73.3 N.A. 13.3 6.6 N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 16 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 16 0 0 0 16 8 0 0 0 0 % D
% Glu: 24 31 0 8 8 39 8 16 0 0 0 0 0 47 8 % E
% Phe: 0 0 0 0 39 8 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 8 0 0 0 0 0 0 8 8 0 0 0 0 47 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 24 47 0 0 % I
% Lys: 0 0 0 8 0 0 8 0 31 0 0 0 0 0 0 % K
% Leu: 0 0 0 16 8 8 8 0 16 8 0 0 0 16 0 % L
% Met: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 47 8 8 39 16 0 39 8 8 47 54 0 16 0 0 % P
% Gln: 8 0 0 8 0 0 8 0 16 0 0 0 8 0 8 % Q
% Arg: 0 8 8 0 0 0 8 0 0 0 0 8 8 0 8 % R
% Ser: 0 0 16 0 8 0 0 47 0 0 0 0 0 0 8 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 8 31 0 0 0 0 0 0 0 0 47 0 8 0 % V
% Trp: 0 0 0 0 0 8 0 0 0 0 16 0 0 8 0 % W
% Tyr: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _