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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RIOK2
All Species:
41.52
Human Site:
Y141
Identified Species:
65.24
UniProt:
Q9BVS4
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BVS4
NP_060813.2
552
63283
Y141
N
L
K
N
K
R
D
Y
H
K
H
R
H
N
V
Chimpanzee
Pan troglodytes
XP_517843
552
63335
Y141
N
L
K
N
K
R
D
Y
H
K
H
R
H
N
V
Rhesus Macaque
Macaca mulatta
XP_001095785
551
63384
Y141
N
L
K
N
K
R
D
Y
H
K
H
R
H
N
V
Dog
Lupus familis
XP_536291
531
60932
Y124
N
L
K
N
K
R
D
Y
H
K
H
R
H
N
M
Cat
Felis silvestris
Mouse
Mus musculus
Q9CQS5
547
62472
Y141
N
L
K
N
K
R
D
Y
H
K
H
R
H
N
V
Rat
Rattus norvegicus
NP_001009687
551
62702
Y141
N
L
K
N
K
R
D
Y
H
K
H
R
H
N
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512597
627
71085
Y218
N
L
K
N
K
R
D
Y
H
R
H
R
H
K
M
Chicken
Gallus gallus
NP_001006581
551
63395
Y141
S
L
K
N
K
R
D
Y
H
K
H
R
H
K
M
Frog
Xenopus laevis
NP_001086801
548
62044
Y141
N
L
K
N
K
R
D
Y
H
K
H
R
H
K
M
Zebra Danio
Brachydanio rerio
NP_998719
512
58691
R129
L
K
L
H
R
L
G
R
T
S
F
R
N
L
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651365
538
61413
Y141
N
V
K
A
K
R
D
Y
H
G
R
R
H
K
A
Honey Bee
Apis mellifera
XP_623367
426
49113
V49
A
N
L
R
Y
G
G
V
H
K
L
L
K
E
L
Nematode Worm
Caenorhab. elegans
NP_493544
529
60467
Y141
K
I
K
E
K
R
D
Y
H
K
K
R
K
S
A
Sea Urchin
Strong. purpuratus
XP_784439
491
55586
E114
T
S
F
R
K
L
K
E
K
R
D
Y
L
G
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P40160
425
49106
G48
S
G
M
R
S
Q
S
G
T
N
R
A
I
S
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
96.5
81.6
N.A.
82.9
81.6
N.A.
62.5
65.5
67.2
67.3
N.A.
44.3
47.6
41.8
49.4
Protein Similarity:
100
99.6
98.7
88.5
N.A.
91.3
90
N.A.
72
79.1
80
77.9
N.A.
62.6
62.8
60.1
65
P-Site Identity:
100
100
100
93.3
N.A.
100
100
N.A.
80
80
86.6
6.6
N.A.
60
13.3
53.3
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
93.3
93.3
93.3
26.6
N.A.
66.6
20
66.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
31.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
48.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
7
0
0
0
0
0
0
0
7
0
0
14
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
74
0
0
0
7
0
0
0
7
% D
% Glu:
0
0
0
7
0
0
0
7
0
0
0
0
0
7
0
% E
% Phe:
0
0
7
0
0
0
0
0
0
0
7
0
0
0
0
% F
% Gly:
0
7
0
0
0
7
14
7
0
7
0
0
0
7
0
% G
% His:
0
0
0
7
0
0
0
0
80
0
60
0
67
0
0
% H
% Ile:
0
7
0
0
0
0
0
0
0
0
0
0
7
0
0
% I
% Lys:
7
7
74
0
80
0
7
0
7
67
7
0
14
27
14
% K
% Leu:
7
60
14
0
0
14
0
0
0
0
7
7
7
7
7
% L
% Met:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
27
% M
% Asn:
60
7
0
60
0
0
0
0
0
7
0
0
7
40
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
20
7
74
0
7
0
14
14
80
0
0
0
% R
% Ser:
14
7
0
0
7
0
7
0
0
7
0
0
0
14
0
% S
% Thr:
7
0
0
0
0
0
0
0
14
0
0
0
0
0
0
% T
% Val:
0
7
0
0
0
0
0
7
0
0
0
0
0
0
34
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
7
0
0
74
0
0
0
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _