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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RIOK2
All Species:
22.35
Human Site:
S548
Identified Species:
35.12
UniProt:
Q9BVS4
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BVS4
NP_060813.2
552
63283
S548
K
S
S
L
E
A
A
S
F
W
G
E
_
_
_
Chimpanzee
Pan troglodytes
XP_517843
552
63335
S548
K
S
S
L
E
A
A
S
F
W
G
E
_
_
_
Rhesus Macaque
Macaca mulatta
XP_001095785
551
63384
S547
K
S
S
M
E
A
A
S
F
W
G
E
_
_
_
Dog
Lupus familis
XP_536291
531
60932
S527
K
S
S
L
E
A
A
S
F
W
G
E
_
_
_
Cat
Felis silvestris
Mouse
Mus musculus
Q9CQS5
547
62472
S543
K
S
S
L
E
A
A
S
F
W
G
D
_
_
_
Rat
Rattus norvegicus
NP_001009687
551
62702
S547
K
S
S
L
E
A
D
S
F
W
G
D
_
_
_
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512597
627
71085
Chicken
Gallus gallus
NP_001006581
551
63395
Frog
Xenopus laevis
NP_001086801
548
62044
Zebra Danio
Brachydanio rerio
NP_998719
512
58691
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651365
538
61413
Honey Bee
Apis mellifera
XP_623367
426
49113
Nematode Worm
Caenorhab. elegans
NP_493544
529
60467
A523
K
D
N
K
D
V
I
A
E
Y
A
G
W
I
_
Sea Urchin
Strong. purpuratus
XP_784439
491
55586
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P40160
425
49106
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
96.5
81.6
N.A.
82.9
81.6
N.A.
62.5
65.5
67.2
67.3
N.A.
44.3
47.6
41.8
49.4
Protein Similarity:
100
99.6
98.7
88.5
N.A.
91.3
90
N.A.
72
79.1
80
77.9
N.A.
62.6
62.8
60.1
65
P-Site Identity:
100
100
91.6
100
N.A.
91.6
83.3
N.A.
0
0
0
0
N.A.
0
0
7.1
0
P-Site Similarity:
100
100
100
100
N.A.
100
91.6
N.A.
0
0
0
0
N.A.
0
0
42.8
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
31.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
48.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
40
34
7
0
0
7
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
0
0
7
0
7
0
0
0
0
14
0
0
0
% D
% Glu:
0
0
0
0
40
0
0
0
7
0
0
27
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
40
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
40
7
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
7
0
0
0
0
0
0
7
0
% I
% Lys:
47
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
34
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
40
40
0
0
0
0
40
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
40
0
0
7
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
40
40
47
% _